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Biomedical subjects

B Favre

Publications and source records attributed to B Favre.

41 records · Page 3Linked to original sources
PubMed1975

[The nature and importance of weight loss during restraint stress in the growing rat (author's transl)].

From general considerations on pig farming, we have noted the experimental advantage presented by the analogy between the pig and the rat concerning the reaction to restraint stress. This sort of stress undergone during transportation results in an appreciable increase in the weight loss in pigs and the purpose of this study was to show that the same applies to the rat. By direct weighing in one hand by measurement of the gaseous exchanges between the animal and its surroundings atmosphere in the other hand, we observed an increase of about 45 p. 100 in the weight loss after 3 hours restraint. 80-90 p. 100 was due to the cutaneous and respiratory emission of water vapor, the remainder was due to the difference between the weight of carbonic gas expired and that of oxygen inspired. Over a 7-hour period of stress the intake of oxygen increased by 60 p. 100 whereas the respiratory quotient decreased more rapidly than in rats not restrained. These results are discussed with relation to the various metabolism involved in stress reaction.

Animals↗
PubMedDate not supplied

French multi-centric study of 2000 amniotic fluid interphase FISH analyses from high-risk pregnancies and review of the literature.

This prospective and multi-centric study confirms the accuracy and the limitations of interphase FISH and shows that any cytogenetics laboratory can perform this technique. With regard to the technical approach, we think that slides must be examined by two investigators, because the scoring may be subjective. The main problem with the AneuVysion kit concerns the alpha satellite probes, and especially the chromosome 18 probe, which is sometimes very difficult to interpret because of the high variability of the size of the spots, and this may lead to false negative and uninformative cases. The best solution would be to replace these probes by locus-specific probes. Concerning clinical management, we offer interphase FISH only in very high-risk pregnancies or/and at late gestational age because of the cost of the test. We think that an aberrant FISH result can be used for a clinical decision when it is associated with a corresponding abnormal ultrasound scan. In other cases, most of the time, we prefer to wait for the standard karyotype.

Adult↗