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Biomedical subjects

B Farrell

Publications and source records attributed to B Farrell.

42 records · Page 3Linked to original sources
PubMed1979

Nitrous oxide-induced myelopathy-neuropathy: potential for chronic misuse by dentists.

The myelopathy and neuropathy associated with chronic misuse of nitrous oxide are potentially reversible if the habit is discontinued. This occurred in each of the reported cases, including our case, when it was transiently discontinued. Although a causal relationship between nitrous oxide and this myelopathy-neuropathy has not been proved, the circumstantial evidence is convincing. Both physicians and dentists should be aware of this potentially serious complication of chronic self-administration of nitrous oxide, especially in persons inclined to misuse drugs. Dentists, with their access to nitrous oxide, may be particularly at risk.

Adult↗
PubMedDate not supplied

Bird fanciers' lung: a case report.

The clinical course of a case of bird fanciers' lung is described along with the considerations that are important in the management of this form of hypersensitivity pneumonitis. Diagnostic parameters, therapeutic considerations, and environmental issues are discussed in the context of the current literature.

Anti-Inflammatory Agents↗
PubMedDate not supplied

Longterm effects of early cadmium exposure on locomotor activity in the rat.

The present study investigated the hypothesis that changes in the frequency of specific behaviors, not assessed by the traditionally employed global measures of locomotor activity, may occur following exposure to cadmium. Two groups of newborn male rat pups were treated orally with either 1.0 mg/kg CdCl2 for 14 days or 10.0 mg/kg CdCl2 for one day followed by 13 days of the treatment vehicle only. A control group received only the vehicle. At 50 days of age, animals were observed in their home cage for 12 hours and the amount of time spent engaged in each of eight separate categories of behavior was recorded. Subsequently, exploratory behavior in an open field was assessed. The single large dose of cadmium resulted in weight loss and a significantly slower growth rate significantly increased rearing in the home cage and significantly decreased inner square exploratory behavior in the open field. Implications of emotional hyporeactivity and physiological explanations which may account for the differences observed between the two treatment regimens are discussed.

Animals↗