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Biomedical subjects

B Fallon

Publications and source records attributed to B Fallon.

At least 37 records · Page 2Linked to original sources
PubMed1984

Cryotherapy.

Since 1969 cryosurgical perineal destruction of the prostate has been developed at the University of Iowa for treatment of patients with prostatic cancer. The technique of this procedure has been the subject of previous reviews. This is a summary of our experience of patient survival and the effect on local prostatic cancer growth in those patients with various stages of the disease subjected to perineal cryosurgical destruction of their cancer. We also report briefly on our experience in the laboratory where the Dunning tumor model is used to study the effect of cryosurgery as well as combinations of immunological modifications.

Adult↗
PubMed1984

Long-term followup in patients with an inflatable penile prosthesis.

An inflatable penile prosthesis was implanted in 95 patients between 1977 and 1983. The patients were divided into 3 groups with roughly equal numbers studied during 2-year intervals. Of the prostheses 48 per cent have been revised or removed, or have failed during followup. The complication rate increased with the duration of followup.

Adult↗
PubMed1984

Urological manifestations of patients with visceral myopathy.

Of 10 patients with familial or nonfamilial visceral myopathy studied for urological manifestations only 3 had symptoms of urinary retention. Excretory urography revealed megacystis in all 3 symptomatic patients, while the 7 asymptomatic patients had normal-sized bladders. Cystometrograms performed in 4 asymptomatic patients also were normal. Bladder tissue from 5 patients was studied. Of 3 autopsy cystectomy specimens 2 were dilated severely and thin-walled without trabeculations or diverticula suggestive of mechanical obstruction. Microscopic sections showed segmental intrafascicular fibrosis in 4 patients, which was associated with elastosis in 3. Electron microscopy of leiomyocytes in abnormal fascicles revealed myofilament disorganization, lipid accumulation and increased numbers of cytoplasmic organelles. We conclude that pathological changes in the bladder occur commonly but urinary symptoms occur in less than half of the patients with visceral myopathy available for study. An abnormal excretory urogram was seen in only patients who had symptoms suggestive of lower urinary tract dysfunction.

Adolescent↗
PubMed1984

Urological injury and assessment in patients with fractured pelvis.

Of 200 patients with pelvic fractures 32 (25 male and 7 female patients) had urological injury. Of these 32 patients 31 had pubic ramus or symphyseal fractures: 29 had gross hematuria and a urine specimen was not obtained in 2. Only 1 of 77 patients with microscopic hematuria had serious urological injury. We believe that excretory urography is not necessary in all cases of pelvic fracture, and that urethrography and cystography are indicated only in cases of gross hematuria or when other clinical signs indicate a high likelihood of bladder or urethral trauma.

Adolescent↗
PubMed1984

Experience with the Jonas penile prosthesis.

Between April 1981 and June 1983 the Jonas penile prosthesis was inserted in 57 patients. There were 10 early complications (17.5 per cent), with 8 operations for revision or removal (14 per cent). Late complications were rare and the over-all success rate was 96 per cent.

Adult↗
PubMed1983

Cryosurgery in prostatic cancer: elimination of local lesion.

From 1969 through 1976, we performed cryosurgery in 229 cases of prostatic cancer. Most of these patients had bulky, locally extensive primary tumors, and one-half had disseminated disease. Through the open perineal approach, which gives exposure for an adequate freeze, cryosurgery has been well tolerated. The primary surgical goal has been to reduce or eliminate the local lesion to minimize subsequent cancer-related lower urinary tract problems and to cure those patients with truly localized disease. In every case cryosurgery produced dramatic shrinkage of the local lesion. After four to eight weeks a local recurrence was suspected in 13 per cent, and 41 per cent eventually had some evidence of a recurrent cancer nodule or persistent cancer in the bladder neck. In a series of statistical analyses we have related these recurrences to other clinical factors. Cryosurgery has been a safe, effective way to reduce or eliminate the primary prostatic cancer, even in patients with large local lesions.

Aged↗
PubMed1983

Ureterovesical reflux in an adolescent and adult population.

The records and radiographic data on 177 adolescents and adults with vesicoureteral reflux were reviewed. The anatomic characteristics of 255 renal units and ureterovesical junctions were characterized using criteria reported previously. A total of 125 renal units demonstrated grades III to V reflux (International). Abnormal ureteral orifices were observed in 145 renal units and 155 submucosal tunnels were short or absent. Excretory urograms outlined renal scars in 192 renal units. Pre-treatment and post-treatment creatinine clearances were analyzed in 188 renal units. Ureteral reconstruction resulted in stabilization or improvement in the mean creatinine levels in 53 renal units. Other forms of surgical and medical treatment also resulted in improved renal function during observation.

Adolescent↗
PubMed1982

Cryosurgery in prostatic cancer: survival.

From 1969 through 1976 we performed cryosurgery in 229 cases of prostatic cancer. This article presents survival in cryosurgery and other treatment groups. In every stage, despite a preponderance of large primary tumors and poor-risk patients, cryosurgery matched total prostatectomy and compared favorably to other modalities, including radiation therapy, at our center and elsewhere. According to previous authors, and in view of the present data, eradication of the local lesion is associated with better survival even in advanced cases. Cryosurgery provides a safe, effective method.

Aged↗
PubMed1982

Tuberculous stricture of ureter.

Tuberculous stricture of the ureter is not uncommon in centers which treat large numbers of patients with urinary tuberculosis. Ninety-seven such strictures were seen in 92 patients over a twenty-five-year period. All patients were treated with appropriate antituberculous chemotherapy. Transurethral dilatation of the ureteral stricture was done on 80 ureters. Dilatation was successful in 51 ureters (64%) and failed to relieve the strictures in 29. Technical difficulties prevented dilatation of 17 ureters. We believe that transurethral dilatation should be attempted on all tuberculous ureteral strictures and that other procedures should be employed only if dilatation fails.

Adolescent↗
PubMed1982

Congenital anomalies associated with cryptorchidism.

We reviewed 334 patients with cryptorchidism treated at our institution during a 13-year period. Other congenital anomalies were apparent on physical examination in 102 cases and these were more common in patients with bilateral cryptorchidism. Of the 205 excretory urograms done 25 showed abnormalities and, again, these abnormalities were noted more commonly in patients with bilateral cryptorchidism. Of 232 patients with asymptomatic cryptorchidism, that is with no other congenital findings on physical examination, 141 had an excretory urogram and 4 revealed some abnormality, 2 of these warranting surgical intervention. Of the 334 patients 16 had hypospadias and 50 were mentally retarded. The literature is reviewed. It is concluded that an excretory urogram is not justified on a routine basis in patients with asymptomatic cryptorchidism.

Abnormalities, Multiple↗
PubMed1981

Renal carbuncle: diagnosis and management.

Six cases of renal carbuncle are presented. Nonstaphylococcal carbuncles now greatly outnumber those of staphylococcal origin. Diagnostic modalities are discussed. No radiologic or laboratory investigation is specific, but the diagnosis should be suspected in most cases if adequate attention is given the patient's signs and symptoms. Surgical treatment is recommended.

Adolescent↗