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Biomedical subjects

B F Jones

Publications and source records attributed to B F Jones.

At least 19 recordsLinked to original sources
PubMed1991

Acute renal failure due to acute pyelonephritis.

We report a case of biopsy-proved acute pyelonephritis which caused acute renal failure. Despite appropriate antibiotic therapy, recovery of renal function was slow and incomplete. Renal papillary necrosis was an apparent complication, which the patient may have been predisposed to by alcoholism. Although rare, acute pyelonephritis is an important consideration in the differential diagnosis of acute renal failure because of the need for specific therapy.

Acute Kidney Injury↗
PubMed1990

Analysis of videotaped consultations to certify competence.

The assessment of videotaped genuine consultations in order to provide feedback to the learner is now a well accepted part of postgraduate training for general practice. This article reports on a pilot study which investigates the adaptation of videotape assessment of genuine patient consultations as an alternative to the present simulated patient interview segments of the examination for Fellowship of the Royal Australian College of General Practitioners. In particular, the study addresses: the feasibility and cost of collecting and assessing a suitable range of videotaped consultations using portable videocamera equipment and remote examiners; the interobserver reliability of four independent examiners; and the correlation between scores on two different rating scales. The results demonstrate that the assessment of videotaped genuine consultations has the potential to become a means of end-point assessment of clinical competence. The problem of how to collect videotapes of a suitable range and number of consultations to permit a candidate to demonstrate proficiency needs to be addressed and will be followed up in a trial of the method during 1990.

Australia↗
PubMed1989

Xanthogranulomatous pyelonephritis in a renal allograft: a case report.

We report a case of xanthogranulomatous pyelonephritis in a renal allograft. The kidney was not removed and there was an initial response to antibiotic therapy, with amelioration of toxicity and improvement in renal function. However, the kidney failed 10 months later in association with histological changes of chronic rejection.

Anti-Infective Agents, Urinary↗
PubMed1985

Fracture of the cervical spine in ankylosing spondylitis.

The radiological features, clinical findings and mortality rates of patients with ankylosing spondylitis complicated by cervical trauma have been reviewed. All patients had long-standing disease and half had sustained their fractures as a result of trivial accidents. There were 19 cervical fractures in 18 patients, which were chalkstick in type and occurred predominantly at the 6th and 7th cervical levels. Ten fractures passed through the upper part of the vertebral body, one through the mid-vertebral body and the final eight were through the disc space. The site of the fracture line was related to neurological outcome. Those patients whose fracture line ran through the disc space had significantly less neurological injury and a much better prognosis. Distraction at the fracture site had some relation to prognosis but horizontal displacement and angulation were not found to be of importance. This study confirms that cervical fracture with neurological complications may follow minor trauma in ankylosing spondylitis. The site of the fracture in relation to the vertebral bodies and discs appears to be of some prognostic relevance and careful radiological assessment of all patients with ankylosing spondylitis and cervical injury should be undertaken.

Adult↗
PubMed1983

Post-obstructive diuresis.

A patient with post-obstructive diuresis is described. Inappropriate losses of salt and water occurred, with urine volume exceeding half the glomerular filtration rate. Additionally, excessive urinary excretion of potassium, bicarbonate, calcium, phosphate, magnesium and urate took place in the presence of subnormal blood levels. Transient proteinuria was also observed. This case demonstrates that serious electrolyte disturbances can occur after relief of urinary tract obstruction and the evidence suggests these may be due to disordered proximal tubule function.

Diuresis↗
PubMed1982

Unusual radiological changes associated with probable Bartter's syndrome.

We report 2 cases that fulfill some of the criteria for the diagnosis of Bartter's syndrome and were associated with marked radiological changes. Both patients demonstrated distortion of the caliceal pattern with medullary cavities and loss of cortical substance in the absence of vesicoureteral reflux. However, the glomerular filtration rate was well preserved. It seems unlikely that known organic renal disease was responsible for these changes and the potassium-losing state. These radiological findings also do not appear to be a consequence of hypokalemia and their pathogenesis remains uncertain.

Adult↗
PubMed1979

Impairment of acute protein reactivity in chronic renal failure.

The acute phase protein response was studied after elective surgery in 13 normal subjects and 9 patients with severe chronic renal failure. Total haemolytic complement reactivity (CH50) and serum concentrations of C1q, C1s, C4, C3, factor B, properdin, C5, C9, C-reactive protein (CRP), caeruloplasmin, alpha1-acid glycoprotein and haptoglobin were measured preoperatively and on days 2, 4 and 6 after operation. Abnormalities were seen in the group with chronic renal failure. Firstly, there was no significant acute phase response of C1s, C3, C5, C9 and CH50 and a significant reduction in the response of factor B. Secondly, CRP showed prolonged elevation in the post-operative period in contrast to the transient rise seen in the control group. With the possible exception of alpha1-acid glycoprotein, the behaviour of the non-complement proteins (caeruloplasmin and haptoglobin) was comparable for the two groups. These defects could impair the physiological response to infection in patients with severe chronic renal failure.

Adult↗
PubMed1976

Clinical evaluation of a dialysate regeneration system for maintenance haemodialysis.

A commercially available sorbent-based dialysate regeneration system has been compared to conventional single-pass dialysate delivery systems for treatment periods of six weeks in 13 patients on maintenance dialysis. The results of treatment were virtually identical in comparing sorbent and conventional systems except that seven of the eight patients using 2-5 M2 dialysers for 3--4 hours thrice per week developed asymptomatic metabolic acidosis with the dialysate regeneration system. This complication was not seen in the five patients using 1-3 M2 dialysers and having a 6--7 hour treatment thrice weekly. Dialysate regeneration systems are particularly suited for use when water supplies are limited or of insufficient purity for single-pass dialysis, and when a portable artificial kidney is required. To avoid metabolic acidosis with this system, using currently available disposable cartridges, each dialysis treatment should be of at least 4-5 hours duration.

Acidosis↗