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Biomedical subjects

B F HOFFMAN

Publications and source records attributed to B F HOFFMAN.

At least 19 recordsLinked to original sources

REVERSIBLE COLD BLOCK OF THE SPECIALIZED CARDIAC TISSUES OF THE UNANAESTHETIZED DOG.

The sinoatrial node and the bundle of His in intact, unanesthetized dogs were subjected to local cooling by means of surgically implanted devices. Impulse formation in the sinoatrial node could thus be suppressed at will and the heart rate regulated within a physiological range by an electrode driving the atrium. Reversible blockage of atrioventricular conduction was easily induced on cooling the region of the bundle of His.

Bundle of His↗