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Biomedical subjects

B F Farber

Publications and source records attributed to B F Farber.

38 records · Page 3Linked to original sources
PubMed1980

Postoperative wound infection rates: results of prospective statewide surveillance.

The results of a prospective statewide study of postoperative wound infection rates after 19 selected surgical operations are reported. Rates are based on 44,689 operations performed at 38 hospitals from January 1, 1977 through May 31, 1979. The data were collected by review of ward charts and are compared with those of earlier reports. Particularly high rates of infection were found after surgery for perforative appendicitis, colorectal resection, radical neck dissection and leg amputations. These rates should serve as a baseline for future comparisons. The potential value of centralized infection reporting is discussed.

Hospital Bed Capacity, 100 to 299↗
PubMedDate not supplied

Enterococcal endocarditis: a comparison of prosthetic and native valve disease.

Between 1973 and 1987, 36 patients with 41 episodes of enterococcal endocarditis were seen at our institution. There were 22 episodes of native valve endocarditis (NVE) and 19 episodes of prosthetic valve endocarditis (PVE). The overall mortality before completion of therapy was 15% (18% due to NVE and 11% due to PVE). Among patients with NVE, involvement of the aortic valve was significantly associated with death or complicated illness (defined as the need for valve replacement before completion of antibiotic therapy or relapse of endocarditis after completion of therapy). Among patients who survived episodes of PVE, 69% were cured without surgical intervention. Gentamicin was administered in combination with a penicillin or vancomycin in the majority of episodes (mean duration of therapy with aminoglycosides: 5 weeks). Renal dysfunction occurred in 44% of patients who received gentamicin and occurred more frequently in patients with elevated serum creatinine levels before treatment. Our results suggest that enterococcal PVE can often be successfully treated with antibiotics alone, and they confirm the efficacy of gentamicin when it is administered in combination with cell wall-active agents for the treatment of endocarditis due to enterococci that lack high-level resistance to this agent.

Adult↗