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Biomedical subjects

B F Ericsson

Publications and source records attributed to B F Ericsson.

At least 37 records · Page 2Linked to original sources

The arm-ankle pressure gradient in relation to cardiovascular risk factors in intermittent claudication.

The arm-ankle systolic pressure gradient was measured in 165 male patients with intermittent claudication and was correlated with different combinations of known cardiovascular risk factors. The pressure gradient increased with increasing number of risk factors. We conclude that intermittent claudication may be used as a simple model for studies of arteriosclerosis, the arm-ankle systolic pressure gradient being a measure of the degree of arteriosclerosis between heart and ankle.

Adult↗

Reconstruction of the carotid artery. A review of 167 operations.

During an 8-year period 149 patients underwent 167 carotid operations. TIA or amaurosis fugax was the operative indication in 60% of the cases and TIA-IR (minor strokes) in 25%. The operative mortality was 4.2%. New neurological permanent deficits appeared in connection with the operation in 4.2%. They were all of benign character. The mean follow-up time was 23 months with a range from 4 months to 8 years. The postoperative follow-up revealed a 10% frequency of strokes during a 6-year period, i.e. 1.6% per year. The 5-year survival for the whole material was 71% and for patients without signs of coronary artery disease, operative mortality excluded, it was identical with the 5-year survival for the "normal population" in the same area, i.e. 85%.

Aged↗

Aortoduodenal fistula after surgery for renal artery stenosis.

An unusual case of aortoenteric fistulation, 5 years after surgery for renal artery stenosis, is presented. A stenotic right renal artery had been reimplanted into the aorta in a 4 1/2 year old boy. No signs of infection had been present, nor had any synthetic material been used. The fistula was found to originate from the ligated renal artery, not from the reconstruction. It was successfully corrected without compromising the kidney.

Aortic Diseases↗

Unilateral renal artery stenosis and hypertension. II. Angiographic findings correlated with blood pressure response after surgery.

The findings at preoperative nephroangiography of 42 hypertensive patients with unilateral renal artery stenosis or occlusion were correlated with the blood pressure response following surgery and also with the preoperative renal vein renin activity ratio. A stenosis reducing luminal area by at least 90 per cent (or occlusion) and the presence of collateral circulation are considered to be highly suggestive of renovascular hypertension.

Adolescent↗

Technique and complications in the surgical treatment of renovascular hypertension.

147 operations for renovascular hypertension were performed in 125 patients. 136 of the operations were vascular reconstructions. Aortorenal by-pass, using saphenous vein as a graft, was found to be a satisfactory technique. An aneurysmatic dilatation developed twice, which on both occasions was attributed to a stenosis proximal to the graft. Two failures also occurred among the 12 patients undergoing renal autotransplantation, both due to an illiac vein thrombosis, obstructing the renal vein. The majority of the six deaths were due to myocardial infarctions or uremia. They all occurred in the eldest patients (older than 59 years) and in patients suffering from complicating cardiac or renal disease. The results with regard to blood pressure were very good in fibrous dysplasia and in atherosclerosis affecting only one side. Operative treatment can therefore be recommended to these groups of patients even in relatively mild hypertension. The indication to operate should be restricted in elderly patients suffering from cardiac and renal complicating diseases, and in patients with bilateral atherosclerotic stenosis.

Adolescent↗

Bilateral renal artery stenosis/occlusion and renovascular hypertension. Correlation of angiographic findings with blood pressure response after surgery.

In a previous study of unilateral renal artery stenosis the angiograms of patients with a favourable blood pressure response after surgery were found to be characterized by a reduction of renal arterial lumen greater than or equal to 90% and/or renal collateral circulation. Ancillary features were post-stenotic dilatation and a reduction of kidney length greater than or equal to 1 cm (Andersson; Andersson, Bergentz, Dymling, Ericsson, Hansson & Hökfelt). This report deals with 32 patients with bilateral renal artery stenosis who were followed 6--54 months after operation. The preoperative angiograms were analysed retrospectively without knowledge of the blood pressure response. In patients with bilateral fibromuscular dysplasia a good correlation was found between the above-mentioned criteria and a favourable blood pressure respone. In patients with bilateral arteriosclerotic stenosis no correlation was found. It was concluded that renal angiography constitutes a valuable predictive test in bilateral non-arteriosclerotic stenosis. In the presence of bilateral arteriosclerotic stenosis the selection of patients for surgery should be based on other parameters such as kidney function, age and general vascular status of the patient.

Adult↗

Survival in burned mice after treatment with tryglycylvasopressin.

Standardized skin burn injuries were induced in 253 NMRI mice. The burned surface corresponded to 15% of the total surface of a 25-gram mouse. All animals received intraperitoneal injection of an isotonic saline solution in a dose of 20% of body weight/day for 5 days. The material was divided into three groups, i.e. group A (controls) which received no further treatment, groups B and C which, in addition, received triglycylvasopressin (a vasopressin with prolonged effect) 100 and 200 mug/kg body weight, respectively, subcutaneously twice a day. The highest survival rate was registered in group B (61%), while the controls had a survival of 36%.

Animals↗

Bilateral fibromuscular hyperplasia in the internal carotid arteries with aneurysm formation.

A patient with bilateral fibromuscular hyperplasia in the carotid arteries with development of aneurysms is reported. The patient had no symptoms except for a palpable mass on one side and a bruit on both sides. Surgery was carried out bilaterally, using direct end-to-end suture on one side and a reconstruction with an autologous vein on the other side. It is suggested that fibromuscular hyperplasia may be the cause of some of the internal carotid artery aneurysms reported as congenital or with uncertain etiology. Reconstructive surgery of the carotid artery is recommended due to the obvious hazards of the condition.

Aneurysm↗