Biomedical subjects
Publications and source records attributed to B F Barker.
Ameloblastic fibrosarcoma is an extremely rare tumor. To date only 43 cases have been reported in the literature. An additional case of ameloblastic fibrosarcoma is presented; the clinical features, histologic characteristics, treatment, and the relevance of the presence of dental hard tissue are discussed.
An air-powder abrasive system, the Prophy-Jet, is a commercially available product product intended for use during dental prophylaxis procedures. The purpose of this investigation was to assess the effects on periodontal tissues when the device is used as an adjunct to hand instrumentation in root preparation during periodontal surgery. The degree of tissue injury was assessed by evaluating clinical healing and by histometric analysis of the intensity of the inflammatory response at selected healing times. Surgical sites subjected to Prophy-Jet treatment tended to have slightly lower histometric inflammation scores than control sites treated by hand instrumentation alone. As judged by the inflammatory response and clinical healing, additional effects to surgical exposure of tissues of the periodontium were benign. Use of the Prophy-Jet instrument during periodontal surgery is effective and well tolerated.
Hyaline ring-like structures are often encountered during microscopic evaluation of inflamed tissues from the oral cavity. The exact etiology remains unknown. Two theories exist. One favors intrinsic origin, most likely collagen, while the other suggests extrinsic origin, vegetable material. The literature is reviewed and histologic features are illustrated.
In human beings, the viral origin of condylomatous lesions of the mouth and cervix, multiple papillomas, and verruca vulgaris of the larynx has been established. The viral origin of papillomatosis in rabbits and dogs has also been documented. The literature, however, shows no conclusive evidence of a viral origin of human oral squamous cell papillomas (SCP). The purpose of this study was to use the peroxidase-antiperoxidase (PAP) staining technique to determine whether human papillomavirus (HPV) antigens exist in serial step sections of human oral SCP. Fifty human oral SCPs were randomly selected from the department files, and tissue sections were subjected to an indirect immunoperoxidase-PAP technique. Evidence of HPV-Type I virus antigens was found in 2 of 50 papillomas studied (2 of 194 tissue sections). This suggests that all oral SCPs are not of viral antigen.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A case of gingival fibromatosis with hypertrichosis is reported in a 3-year-old girl. Partial recurrence was observed 6 months after surgical treatment. Psychological benefits resulting from the cosmetic improvement may outweigh the probability of recurrences in this rare condition.
Diagnostic problems within the oral cavity may be associated with lesions of the odontogenic apparatus, salivary glands, bone, mucosa, and connective tissue. Some lesions are unique to the oral cavity, others have a systemic distribution. Several unique and controversial lesions have been selected for discussion, including (1) necrotizing sialometaplasia, a benign salivary gland disease easily mistaken for malignancy; (2) verrucous lesions including verrucous carcinoma, verrucous hyperplasia, and papillary carcinoma; (3) spindle-cell carcinoma, which is often confused with sarcoma; (4) named and unnamed embryonic rests, which may resemble metastatic carcinomas; (5) dental pulp mistaken for odontogenic myxoma; and (6) granular cell tumor with associated pseudoepitheliomatous hyperplasia.
Two examples of central odontogenic fibroma, WHO type, are reported. The radiographic and microscopic features are discussed and illustrated. Both were treated by curettage, and neither has recurred after 10 and 9 years, respectively. We postulate an ectomesenchymal-epithelial interaction in the histogenesis of this unusual tumor.
Two cases of myospherulosis are reported. The history, histopathology, and nature of this condition are discussed. The placement of antibiotic ointment with a petrolatum base in oral wounds may be of significance. Petrolatum may provoke an inflammatory reaction and remain in tissue for years.
Explore the source record for details and available documents.
This article illustrates the signs and symptoms, diagnostic criteria, and dental treatment for Sjögren's syndrome. Suggestions are offered in the treatment of xerostomia or SS.
Seven examples of an unusual hyalin degenerative change in the walls of blood vessels are discussed. We believe this is a localized phenomenon, not connected to systemic vascular disease. Inflammation is usually present, and in each case a dental procedure had previously been performed. Dental extraction was the most common procedure. Giant cells of the foreign-body type are present, but particulate foreign material was seen in only one case.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Head and neck radiation therapy patients have permanent damage to their salivary glands, tissue, and bone. This damage may result in late effects such as: xerostomia, rampant dental caries, demineralization, trismus, and osteoradionecrosis. Therefore, a pretherapy dental evaluation and treatment and compliance with a long-term oral care regimen are necessary. This retrospective study was designed to assess the late effects of radiation therapy and compliance with long-term care recommendations of patients seen in the Oncology Dental Support Clinic at the University of Missouri-Kansas City School of Dentistry during 1981 to 1989. Telephone interviews of patients and their dentists were conducted, and a written questionnaire to the dentists provided further data. Late effects were consistent with those reported in the literature. A compliance rate of approximately 50% was reported. Several measures have been implemented in an attempt to increase compliance.
The purpose of this investigation was to evaluate and compare four oral lubricants in relation to oral mucosal status, perceived relief of dry mouth symptoms, and patient acceptance. Three commercial oral lubricants--two sprays and one gel--and a home remedy of margarine were evaluated. Twenty-five xerostomic/salivary gland dysfunctional patients demonstrating < 0.20 mL/min of unstimulated whole saliva participated in the randomized, four-phase, cross-over study. Each phase included a ten-day use of oral lubricants, followed by a four-day washout period. On the first and tenth days of use, lip and buccal mucosa dryness and perceived oral dryness were evaluated. Patient acceptance of the oral lubricant was evaluated at the end of each ten-day period. The Wilcoxon matched-pairs signed-rank test was used to analyze data over time and between-group differences. The gel group reported a statistically significant improvement in perceived oral dryness from Day 1 to Day 10. No other significant within-group differences were found. Subjects rated the gel significantly better than margarine for convenience, perceived value, minutes of relief, and in the "overall" rating. No other significant between-group differences were noted.