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Biomedical subjects

B Eurin

Publications and source records attributed to B Eurin.

At least 37 records · Page 2Linked to original sources

[Incidence of biological intravascular coagulation in legal induced abortions].

A prospective study was designed to evaluate coagulation abnormalities induced by early abortion (before ten weeks of pregnancy). Fifty-two women underwent suction abortion, under diazepam-fentanyl anaesthesia with spontaneous ventilation; they were screened for coagulation parameters before and after surgery. Eight tests were carried out: prothrombin time, activated partial thromboplastin time (APTT), thrombin time platelet count, fibrinogen levels, fibrin split products, fibrin soluble complexes and euglobulin lysis time. Results were consistent with activation. Consequences were limited and one general test (APTT) was not significantly modified. Suction abortion, even performed in early pregnancy, exposed to biological disseminated intravascular coagulation with a general risk of venous thrombosis.

Abortion, Induced↗

[Central venous catheterization in pediatric hematology].

Central venous catheters (CVC) have proven to be a reliable route of the administration of chemotherapy, saline, blood cells and nutritional support in patients with malignant haematological disease. However, infection remained one of the most important causes of morbidity associated with this procedure. The aims of this study were a) to evaluate the efficacy of laminar air flow to prevent CVC infections, b) to study morbidity associated with polyethylene (PE) and silicone (S) catheters, and c) to evaluate the part played by increasing staff practice. 177 CVC were inserted in 170 children during a period of 20 months. Ages ranged from 5 months to 15 years (mean: 7 years). All the S CVC were tunnelled whereas, because of their rigidity, none of the PE CVC were. At the time of their removal, bacteriological samples from the CVC skin exit site, blood drawn through the catheter and the tips of these CVC were cultured. During the first period (one year), three groups of CVC were studied: in group 1, 37 S CVC in patients placed in a non-sterile ward; in group 2, 40 S CVC in children nursed under laminar air flow; in group 3, 60 PE CVC in patients of a non-sterile ward. During the second period (8 months), 40 new S CVC were inserted in children nursed in non-sterile wards, but after nursing staff training (group 4).(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗

Blood loss in total hip replacement: extradural v. phenoperidine analgesia.

The effects of phenoperidine and extradural analgesia on blood loss during and after total hip replacement were compared in 41 patients randomly divided into two statistically comparable groups. Mean blood loss in patients who received phenoperidine was 1065 +/- 316 ml and in patients who received extradural analgesia with 0.5% bupivacaine with adrenaline 1:200 000 it was 650 +/- 277 ml (p less than 0.001). There was no significant difference in postoperative blood loss between the two groups. The reduction in blood loss resulting from the extradural block may prove beneficial in decreasing the hazard and cost of blood transfusions and in facilitating autologous transfusion.

Aged↗

[High frequency ventilation by the inter-cricothyroid approach during ENT endoscopy: report on 83 cases (author's transl)].

The value of high frequency ventilation employing the inter-cricothyroid approach was assessed during general anesthesia for endoscopic examination of the upper respiratory tract passages. The technique for introducing the inter-cricothyroid canula, and the ventilatory apparatus, are described, and results exposed as a function of local effects of puncture and the quality of pulmonary ventilation obtained. Advantages, and other indications for the use of this technique, are discussed.

Adult↗

Hemodynamic and metabolic effects of morphine in the critically ill.

To assess the effects of i.v. injection of morphine, 0.5 mg/kg, hemodynamic studies were performed on 24 critically ill patients under controlled ventilation. An esophageal balloon was used to estimate intrapleural pressure and transmural cardiac filling pressures were calculated. After injection of morphine, there were significant decreases in heart rate (13%), cardiac index (18%), stroke index (17%) and arterial pressure (15%) and there was a nonsignificant increase in esophageal pressure (15%). Transmural cardiac filling pressures decreased significantly (21% for the pulmonary wedge pressure); intravascular filling pressures were unchanged. Oxygen consumption decreased significantly, by 21%, in 10 patients with initially elevated oxygen consumption and by 9% in 14 patients with initially normal oxygen consumption. The oxygen extraction ratio was unchanged, suggesting that the decrease in oxygen consumption was caused by decreased oxygen demand rather than by inadequate oxygen delivery. These results indicate that the hemodynamic effects of morphine (0.5 mg/kg) administered to critically ill patients were associated with a significant decrease in oxygen consumption, which probably reflected sedation and analgesia.

Adult↗

[Droperidol. Action on hemodynamic and oxygen consumption changes (author's transl)].

Hemodynamic and oxygen consumption changes following general anesthesia were studied in 11 patients who did and in 11 patients who did not received droperidol at the end of operation. Both group were similar with respect to age, duration of anesthesia, doses of anesthetic drugs, and hemodynamic and oxygen consumption values immediately at the end of operation. The highest oxygen consumption measurements which were selected as representative of the maximal metabolism of the recovery period showed that the following parameters were lower in the droperidol group than in the non-droperidol group: oxygen consumption (162 +/- 12 and 238 +/- 19 ml/min/m2 respectively), cardiac index (3.0 +/- 0.2 and 4.4 +/- 0.4 l/min/m2), mean arterial pressure (11 +/- 6 and 129 +/- 5 torr), stroke index (27 +/- 3 and 46 +/- 4 ml/m2) left ventricular stroke work index (38 +/- 5 and 77 +/- 8 gm/m2) and PaCO2 (39 +/- 2 and 49 +/- 2 torr). The measurements performed after extubation were similar in both groups. These data show a metabolic and hemodynamic stabilizing effect of droperidol during recovery which may be useful in high-risk patients.

Anesthesia↗

[Severe ischemic accidents from ergotism. A report on 3 cases. Value of a new antidote : sodium nitropruside (author's transl)].

The autors describe 3 recent cases of severe ischemic accidents from ergotism affecting different regions. Two of the cases resulted from taking Gynergene (ergotamine tartrate) for a short period, while the other case followed continuous administration of Desernil (Methysergide) for 3 years. The third case was treated at a late stage by continuous peridural anesthesia and various vasodilators without success and led to very severe mutilations in two young women. The third case was treated by continuous infusions of sodium nitropruside (SNP) under hemodynamic control, and recovery was rapid and complete. The value of SNP as an antidote for severe ergotism is discussed, together with its mode of administration, and precautions necessary when prescribing this extremely powerful vasodilator treatment for this indication.

Adult↗