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Biomedical subjects

B Eklöf

Publications and source records attributed to B Eklöf.

At least 73 records · Page 4Linked to original sources

Raynaud's phenomenon in arterial obstructive disease of the hand demonstrated by locally provoked cooling.

Finger systolic blood pressure (FSP) was measured by cuff technique before and after local cooling in three groups of patients (Raynaud's disease (7), subclavian stenoses, (5), thrombo-angiitis obliterans (15)), and in 15 normals. The response to finger cooling registered as a decrease in FSP indicates an increase of digital arterial tone. In all three groups, digital arterial tone increased more than in normals during finger cooling. Patients with Raynaud's disease showed a pathological increase in arterial tone at 23.5 degrees C with closure of the digital arteries at a mean temperature of 18.5 degrees C. The temperature eliciting these phenomena in patients with thrombo-angiitis obliterans was about 7 degrees C lower (16.5 and 11.0 degrees C, respectively). Accordingly, cold sensitivity and Raynaud's phenomena in the two groups may have a different pathophysiological mechanism, namely a pathological arterial tone in Raynaud's disease vs. a normal arterial tone in obliterative diseases acting on a narrow vessel.

Adult↗

Synthetic arterial grafts. III. The outcome in 22 patients with synthetic axillofemoral bypass grafts.

During the 4-year period 1973--76, 22 patients were operated upon with axillofemoral bypass grafts at the Department of Surgery in Lund. They were high-risk patients with severe ischaemia of the leg or previous graft infections. Fourteen of the 22 grafts were well-functioning after the longest observation time of 32 months. The operative procedure is described and postoperative compliations are reviewed. The axillofemoral bypass reconstruction is recommended as an alternative for this category of patients in whom the conventional aortic bifurcation graft is unsuitable.

Aged↗

Abdominal aortic aneurysms: should they all be resected?

A retrospective study has been carried out on 124 consecutive patients with abdominal aortic aneurysms admitted during the period 1960-74. The mortality rate after emergency operation was 56 per cent and after elective operation 15 per cent. As in other vascular centres during these years the mortality rate has decreased among electively operated patients. We have tried to answer two questions: which patients without signs of rupture should undergo operation and which patients with a ruptured aneurysm should not be operated upon?

Aorta, Abdominal↗

Synthetic arterial grafts. I. General complications.

A retrospective study of 113 patients operated upon with synthetic arterial grafts was made. This report reviews our experience during the past 15 years as a basis for evaluation of complications of abdominal aortic surgery and investigation of methods for preventing some of the major complications of grafting procedures. The early mortality, within the first 10 postoperative days, is also discussed. The most usual complications were graft thrombosis and infection.

Adult↗

Synthetic arterial grafts. II. infection complications.

A retrospective study of 91 patients with synthetic arterial grafts was made. The investigation showed that infection of synthetic arterial grafts is a serious and life-threatening complication. Of our 14 infected cases, 5 patients were amputated and 4 patients died. The incidence of infection is significantly increased when the anastomosis is performed through a groin incision. In addition the management of patients with infected graft is discussed and two cases are reported.

Aneurysm↗

Infection complications after thrombectomy in deep venous thrombosis.

In acute iliofemoral vein thrombosis thrombectomy with a temporary AV-fistula is an alternative treatment to induced fibrinolysis and anticoagulation. Reviewing our results we have found an extremely high incidence of wound infections. In 36 patients thrombectomy with temporary AV-fistula has been performed. 31% of these had a postoperative wound infection. The mean hospital stay for the infected patients was 25 days compared to 10 days for the non-infected patients. In 26 patients a second, elective operation with closure of the AV-fistula was performed. 15% of these patients developed postoperative wound infection. The mean hospital stay for the infected patients was 18 days compared to 5 days for the non-infected patients.

Adult↗

Brain uptake of lactate, antipyrine, water and ethanol.

Brain uptake of antipyrine, water and ethanol was studied in rats under normo-, hypo- and hypercapnic conditions. Brain uptake of D- and L-lactate was studied in normal rats. The uptake was determined with the Oldendorf method, using single common carotid arterial injections of a mixture of -14C-labeled test substance and tritiated reference substance. The results demonstrate that L-lactate is taken up by the brain in significant amounts. The results also demonstrate marked differences in the uptakes of antipyrine, water and ethanol. The brain uptake of antipyrine is lower, the brain uptake of ethanol higher, than of water. The brain uptake of all 3 substances was shown not to be affected by changes in cerebral blood flow, although a decrease of brain uptake of antipyrine relative to ethanol was observed during hypo- and hypercapnia.

Animals↗