Search PubMed⌕ Search

Biomedical subjects

B Ehinger

Publications and source records attributed to B Ehinger.

At least 145 records · Page 8Linked to original sources
PubMed1978

Conjunctival bleeding in Osler's disease with associated platelet dysfunction. A case report.

A patient with Osler's disease (hereditary haemorrhagic telangiectasia) was admitted to hospital because of obstinate, profuse conjuctival bleeding occurring without any known preceding rrauma. Extensive examination of the haemostatic mechanism revealed an impaired platelet function reflected in defective platelet aggregation by ADP, collagen adrenalin and defective clot retraction. This platelet dysfunction, whose association with conjunctival telangiectasia was hitherto unknown, impaired the patient's already deficient primary haemostasis following the vascular anomaly and apparently contributed to the severity of the bleeding which could only be checked surgically. The findings seem to warrant investigation of the platelet function in patients with Osler's disease. In the event of platelet dysfunction drugs, such as acetylsalicylic acid (aspirin), indomethacin, dextrans as well as transfusions with bank blood are contraindicated.

Adenosine Diphosphate↗
PubMed1978

[Dynamics of the dilatation of as uteri during birth].

219 partogramms of primipares and 219 partogramms of multipares were analysed retrospectively. Only normal deliveries after normal pregnancies were taken into consideration. Graphs were plotted of time intervalls against the width of the cervix. The mean duration of dilation were 6 hours for multipares and 9 hours for primipares. All phases of first stage of labour were reduced in multipares. The results were compared with observations of other authors.

Cervix Uteri↗
PubMed1977

Ocular melanomas: formaldehyde-induced fluorescence in relation to mortality.

Some ocular malignant melanomas contain enough cysteinyldopa to make them fluorescent when treated with formaldehyde. In 32 ocular malignant melanomas, such fluorescence was seen in 19 cases, which had a slightly, but not significantly, worse prognosis than the 13 cases with no fluorescence. The mixed type of malignant melanoma showed fluorescence significantly more often than the B type. Fluorescence histochemistry thus gives a biochemical classification of the tumor, but not a malignancy prognosis.

Adult↗
PubMed1977

Light evoked release of radioactivity from rabbit retinas preloaded with (3H)-GABA.

Light flashes evoke an increased release of radioactivity in vitro from rabbit retinas preloaded with (3H)-GABA in vivo. Constant light does not affect the release. No light evoked release can be demonstrated from the glia. Pentobarbitone and AOAA depress the evoked release. The results are consistent with GABA being a retinal neuro-transmitter, most likely in a class of amacrines.

Aminobutyrates↗
PubMed1977

Stimulated release of [3H]beta-alanine from the rabbit retina.

The efflux of [3H]beta-alanine from rabbit retina after intravitreal injection has been studied. The site of uptake of [3H]beta-alanine into retina was checked by autoradiography and was found mainly in the inner plexiform layer and in cells with the position of amacrines and in some ganglion cells. When the preloaded retina was stimulated by light flashes and release of radioactivity increased significantly. Chromatography of the superfusate demonstrated a single radioactive spot which cochromatographed with authentic beta-alanine. The efflux of [3H]beta-alanine was affected by raising the K+ concentration. The rate of efflux was also immediately increased when unlabelled beta-alanine or GABA was added to the superfusion medium. Glycine was much less effective. The present study shows that light stimulation releases [3H]beta-alanine from the retina and that beta-alanine may use the same transport system as GABA. This further supports the suggestion that beta-alanine may act as a "false transmitter" replacing GABA in the retina.

Alanine↗
PubMed1977

The effect of experimental uveitis on the uptake of prostaglandin E1 in the rabbit iris-ciliary body.

Disruption of the blood-aqueous barrier in rabbits was elicited by infrared irradiation of the iris or by alpha-melanocyte stimulating hormone (alpha-MSH) given subcutaneously. One group of animals was pretreated with topical imidazole before the injection of alpha-MSH. The aqueous flare response was followed and the rabbits were killed at the expected height of the uveitis. The uptake of 3H-prostaglandin E1 in the iris with the ciliary body was then determined and found to be significantly decreased in the rabbits in which alpha-MSH had caused a severe damage of the blood-aqueous barrier. When alpha-MSH caused a more moderate aqueous flare response the prostaglandin uptake was on the contrary significantly increased. Pretreatment of the animals with topical imidazole enhanced parallelly the prostaglandin uptake and the aqueous flare response to alpha-MSH. Topical imidazole per se was found to increase the accumulation of prostaglandin. The prostaglandin uptake values were, however, unchanged in eyes in which infrared irradiation of the iris induced a moderate flare response.

Administration, Topical↗
PubMed1976

Indoleamine-accumulating neurons in the retina of rabbit, cat and goldfish.

Special neurons accumulating indoleamines have been detected in the retina of rabbit, cat and goldfish. They have their perikarya in the innermost cell row of the inner nuclear layer, among the amacrine cells, and send their processes to various parts of the inner plexiform layer. The distribution of the processes is different in the different animals investigated. The neurons do not correspond to the previously known dopaminergic retinal neurons, which have a different distribution of their terminals and which can be demonstrated with a specially developed technique, simultaneously with the indoleamine-accumulating neurons.

Animals↗