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Biomedical subjects

B E Statland

Publications and source records attributed to B E Statland.

At least 55 records · Page 3Linked to original sources
PubMed1986

Evaluation of the Yellow IRIS. An automated method for urinalysis.

The authors evaluated the Yellow IRIS automated urinalysis instrument (International Remote Imaging Systems, Chatsworth, CA 91311) in terms of its analytic performance as well as its ease of use. The Yellow IRIS is a system using automated intelligence microscopy (AIM), coupled with a dipstick reader and specific gravity module. The instrument can handle up to 30 specimens per hour in the authors' setting as compared with 10 specimens per hour using a full manual urinalysis coupled with microscopic examination. The authors conclude that the Yellow IRIS performed better than the manual method in terms of precision, linearity, and throughput. In addition, the diagnostic yield using this system in terms of abnormal results was higher than would have been picked up by manual analysis alone.

Autoanalysis↗
PubMed1986

Why office testing?

Recently, new technologies have enabled more and more tests to be performed in the doctor's office. The reasons for performing tests in this setting include convenience to the patient, benefit to the physician treating the patient, and advantage to society. Concerns that have arisen with doctor's office testing include problems with ensuring quality, potential conflicts of interest, and an uncertain reimbursement climate.

Ambulatory Care↗
PubMed1986

The role of the hospital laboratory and its personnel in doctor's office testing.

The physician, the vendor of laboratory systems, the dealer, and the clinical laboratorian all play an important role in doctor's office testing. The interaction of these individuals is necessary for the optimal use of doctor's office testing. The laboratorian can work to promote high-quality testing in the office, can assist the physician in deciding what systems to purchase, can develop training programs for those doing tests, and can serve as a back-up facility for additional testing.

Ambulatory Care↗
PubMed1985

Reliability of amniotic fluid surfactant measurements.

A proficiency study designed to assess interlaboratory precision of amniotic fluid surfactant measurements is presented. A total of 31 laboratories participated in the study. The assays includes lecithin/sphingomyelin (L/S) ratio test, the measurement of phosphatidyl glycerol (PG), and the Lumadex-FSI test. L/S ratio values varied from "1.3" to over "5.0" on aliquots derived from the same pool. With only three exceptions, all PG values read as "positive." The interlaboratory agreement for the Lumadex-FSI assay was excellent. With the exception of two values of "46," all the other values were with "47" or "48."

Amniotic Fluid↗
PubMed1985

Abruptio placentae with coagulopathy: a rational basis for management.

Abruptio placentae rarely produces severe maternal complications while the fetus is alive in utero. The advent of fetal death (grade III) indicates a severe form of abruptio placentae and a real risk that an overt coagulopathy might develop (grade IIIB). Overt coagulopathy associated with a live fetus is, however, uncommon. The advent of an overt coagulopathy should be viewed as ominous. Treatment of abruptio placentae with overt coagulopathy should be directed toward obtaining a rapid and atraumatic vaginal delivery. Once delivery has occurred, spontaneous reversal of the coagulopathy can be anticipated. In the opinion of one of the authors (G.S.), the advent of severe consumption coagulopathy and/or uterine inertia is an indication for intravenous therapy with aprotinin. It has been shown that such therapy will limit DIC, reverse fibrinolysis, reawaken uterine activity, and lead to rapid vaginal delivery within 6-8 hours. Aprotinin is not commercially available for clinical use in the United States. Prolongation of the abruption-delivery interval will worsen maternal prognosis. Accordingly, the advent of uterine inertia prior to complete cervical dilatation is an indication for immediate cesarean section in circumstances where aprotinin is not available. Following delivery, the physician should be on the lookout for postpartum hemorrhage, which may necessitate immediate transfusion, the administration of oxytocics, and/or uterine manipulation. Surgical intervention is rarely indicated in such cases. The patient should also be carefully observed over the ensuing days and weeks for the evolution and resolution of complications, such as renal failure, pulmonary insufficiency, and panhypopituitarism.

Abruptio Placentae↗
PubMed1985

The Technicon RA-1000 evaluated for measuring sodium, potassium, chloride, and carbon dioxide.

We evaluated the Technicon RA-1000 "random-access" analyzer for the measurements of sodium, potassium, and carbon dioxide by an indirect potentiometric method (ion-selective electrode) and for chloride by a colorimetric method (mercuric thiocyanate). For various concentrations of control materials the total precision (CV) ranged from 0.9 to 1.2% for sodium, 1.1 to 1.3% for potassium, 1.0 to 1.2% for chloride, and 2.8 to 3.8% for carbon dioxide. The system demonstrated acceptable performance in linearity and carryover. Patients' results from the RA-1000 correlated well with those from the Beckman ASTRA-8. In a study on potential interferences, we found that high concentrations of salicylate and bromide significantly affected measurements of carbon dioxide and chloride, respectively. The RA-1000 requires only 30 microL of sample for all four tests and it offers a high throughout (30 specimens analyzed for the four tests in 25 min). This precise, easy-to-use, random-access analyzer requires minimal maintenance.

Autoanalysis↗
PubMed1985

Performance of five thyroid-function tests by radioimmunoassays with antibodies attached to paramagnetic micro-particles.

We have assessed the analytical and clinical performance of five thyroid-function tests by commercially available radioimmunoassays in which antibodies attached to paramagnetic micro-particles are used (Corning MAGIC assays). We evaluated the methods for measuring thyroxin, triiodothyronine, triiodothyronine uptake, thyrotropin (thyroid-stimulating hormone), and free thyroxin. Precision, patients' results, and clinical correlation of the MAGIC assays were similar to those of the well-established RIAs used as the comparative methods in this study; the MAGIC assays, however, are much faster and easier to perform.

Evaluation Studies as Topic↗
PubMed1985

Determinations of immunoglobulins G, A, and M in the Technicon RA-1000.

We evaluated the Technicon RA-1000 "Random Access" analyzer for the measurements of immunoglobulins G, A, and M in serum by turbidimetry. For various concentrations of serum pools the total CV ranged from 3.0 to 4.5% for IgG, from 3.1 to 3.2% for IgA, and from 4.8 to 5.4% for IgM. The linearity of the standard curves was good in the clinically useful ranges. Results for patients' samples correlated well with those determined with the Beckman Auto ICS (rate nephelometric method). Normal reference intervals (based on data for 200 healthy blood donors) are 7.67 to 16.87 g/L for IgG, 0.87 to 3.89 g/L for IgA, and 0.61 to 2.70 g/L for IgM. The RA-1000 requires only 8 microL for all three tests and can analyze 25 specimens for all three proteins in 37 min. Compared with other methods for immunoglobulin assays, the RA-1000 has higher throughput and offers significant savings in labor and reagent costs.

Autoanalysis↗
PubMed1985

Increased activity of creatine kinase isoenzyme MB in a theophylline-intoxicated patient.

A 78-year-old woman had increased activities of creatine kinase (CK; EC 2.7.3.2) and CK-MB isoenzyme in her serum, associated with severe theophylline intoxication. The time course for CK-MB activity was similar to that from an acute myocardial infarction. Clinical findings, however, including electrocardiograms, did not support the diagnosis of myocardial infarction. We suggest caution in interpreting CK-MB results in severe theophylline intoxication.

Aged↗