I,858 semi quantitative G6PD determinations were done in Mali (mostly in the Point G Hospital, in Bamako). 15.7% of the men and 4.5% of the women had a G6PD deficiency. The age did not affect the incidence of the disease. G6PD deficiency was more frequent among the Sonrais than among the other ethnic groups tested. It did not occur more frequently among subjects having the sickling trait of AC hemoglobinopathy but no G6PD was found among subjects having a major hemoglobinopathy (SS or SC). Severe hemolytic anemia was rather infrequent among adults subjects. Hemolysis was induced by drugs--such as dapsone or niridazole--but it was usually mild and time-limited.

Adolescent↗

PubMedDate not supplied

[Leukocyte count in French people living in Mali].

The authors studied the leucocytes count of 173 French people living in Mali (West Africa) during 4 years. 8.3% of these subjects presented neutropenia under 1,800/mm3, 12.2% had lymphocytosis over 4,000/mm3 and 11.6% hypereosinophilia over 500/mm3. These abnormalities differ considerably from one year to another in the same subject; their frequency does not depend upon the age, the sex, the duration of the stay in Africa. Eosinophilia is secondary to helminthiasis. Neutropenia and lymphocytosis are probably secondary to unknown evironmental factors.

Adult↗

PubMedDate not supplied

[Treatment and prevention of schistosomiasis (author's transl)].

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Animals↗

PubMedDate not supplied

[Epidemiology and pathologic results of chronic carriers state of hepatitis B in Mali].

The HB antigen of the hepatitis B (HB) virus, studied by counter immunoelectrophoresis shows a prevalence of 8.7% in 1,860 rural Malians and 11.3% in 764 blood donors from Bamako. Amongst 1,350 hospitalised patients, no correlation could be established between the HBs antigen chronic carriers state and other infectious diseases, malnutrition or genetic deficiencies. On the other hand, the prevalence of HBs antigen is particularly high in hepatic infections: acute and chronic hepatitis (53.5%), cirrhosis (31.5%) and hepatomas (25.3%). The study of the prevalence of hepatitis B by radioimmunoassay of the HBV seric markers was carried out in: --176 "healthy" town dwellers of which 97.2% were carriers of at least one marker--HBs Ag: 16.5%; anti-HBc alone: 34.1%; anti-HBs: 46.6%--. --30 subjects with cirrhosis--HBs Ag: 66.7%; anti-HBc alone: 10.0%; anti-HBs: 23.3%--. --42 subjects with PHC--HBs Ag: 47.6%; anti-HBc alone: 23.8%; anti-HBs: 28.6%--. The difference in HBs Ag carrier state between patients (cirrhosis and PHC) and controls, cross-matched for sex and age, is highly significative--p = 0,0001--.

Adolescent↗