Biomedical subjects
Publications and source records attributed to B Drobná.
The basic goals of the TOCOEN project (Toxic Organic COmpounds in the ENvironment) are to detect and understand the fate of selected organic pollutants (PAHs, PCBs and PCDDs/Fs mainly) in the environment. The TOCOEN project was established in 1988 as a free association of Czech and Slovak environmental chemists, ecototoxicologists and other environmentalists.
Fifty samples of human blood collected in 1992 from the general human population living in five selected areas of the Slovak Republic (the Michalovce, Velký Krtís and Nitra District, Myjava area and Bratislava) were analysed for polychlorinated biphenyls (IUPAC Nos. 28, 52, 77, 101, 105, 114, 118, 123, 126, 138 (+163), 153, 156, 157, 167, 169, 180 and 189) and some organochlorine pesticides (HCB, gamma-HCH, p,p'-DDE and p,p'-DDT). PCB levels (the sum of the congeners analysed) in serum lipids averaged for all the samples analysed were 1.79 micrograms.g-1 (range: 0.53-9.20 micrograms.g-1, median: 1.33 micrograms.g-1), HCB 5.38 micrograms.g-1 (0.16-23.20 micrograms.g-1, 4.27 micrograms.g-1), gamma-HCH 0.012 microgram.g-1 (< 0.01-0.18 microgram.g-1), p,p'-DDE 6.05 micrograms.g-1 (1.30-34.80 micrograms.g-1, 4.39 micrograms.g-1) and p,p'-DDT 0.27 microgram.g-1 (< 0.01-0.79 microgram.g-1, 0.23 microgram.g-1). About three times higher levels of PCBs were found in the samples from the district where PCB formulations had been produced (the Michalovce District).