Biomedical subjects

B Drayer

Publications and source records attributed to B Drayer.

22 records · Page 2Linked to original sources

PubMedDate not supplied

Assessment of craniocervical junction and atlantoaxial relation using metrizamide-enhanced CT in flexion and extension.

Metrizamide-enhanced computed tomographic (CT) myelography has made it easier to define the relation of the spinal cord to the vertebral canal. A flexion-extension metrizamide-enhanced CT technique has been developed to study the craniocervical junction that refines evaluation of the relation between the spinal cord and the foramen magnum, atlas, and axis. This technique was used to study 15 adults who had had a structurally normal examination of the upper cervical cord and foramen magnum. The average movement of the upper cervical cord was shown to be 1 mm. The advantages of the flexion-extension metrizamide-enhanced CT examination were evident in 10 other patients who had a variety of craniocervical junction pathologies.

Aged↗

PubMedDate not supplied

Examination of the extracranial carotid bifurcation by thin-section dynamic CT: direct visualization of intimal atheroma in man (Part 2).

Examination of the extracranial carotid bifurcation by thin-section computed tomographic (CT) scans after bolus, high-volume contrast enhancement allowed detection of more disease than did arteriograms in six of eight consecutive patients with transient ischemic attacks. In four patients this was on the clinical side of the lesion; in two the disease was in the asymptomatic carotid artery. One patient appeared to show a carotid ulcer; the ulcer was detected on CT. However, at surgery and subsequent histology, the surface of the lesion was endothelialized. The carotid CT examination is performed in the scanner "dead time" between unenhanced and enhanced head CT scans using the same contrast material for both studies. The examinations covers 3-3.6 cm of the carotid bifurcation region. Thin-section CT of the extracranial carotid arteries is a noninvasive examination that on preliminary evaluations appears to have sensitivity at least equal to that of carotid angiography in the detection of intimal disease.

Adult↗

PubMedDate not supplied

Primary intracranial meningeal and spinal hemangiopericytoma: radiologic manifestations.

Meningeal hemangiopericytomas are rare but aggressive tumors. All eight patients in this series developed recurrences, three with distant metastases. In six patients a lytic destructive lesion of bone was evident. CT scans in three patients demonstrated diffusely enhancing lesions. No tumor calcification was present. In five of six patients angiography was characterized by multiple irregular tumor vessels, an intense prolonged blush, and the absence of early draining veins. Differentiation of these tumors from meningiomas is discussed.

Adult↗

PubMedDate not supplied

Clinical trial of iopamidol for lumbosacral myelography.

The results of the initial North American trial of the nonionic, water-soluble contrast medium iopamidol for lumbosacral myelography are reported. The iopamidol was easily visualized by fluoroscopy during introduction, and the radiographic quality of all 12 conventional myelographic examinations was excellent. The diagnoses were herniated nucleus pulposus (seven), traumatic dislocation (one), metastasis (one), and normal (three). One patient had a repeat myelogram with a different hydrosoluble contrast medium 2 months after his iopamidol examination and surgery and showed no radiographic evidence of arachnoiditis. The adverse reactions were all mild and transient: headache (four cases), nausea (two), and leg pain (one). There were no diaphoresis, fever, seizures, hallucinations, agitation, or vital sign changes. Electrocardiography, hematology, and blood chemistries were all normal. In two patients, electroencephalogram changes, three to four bursts of diffuse intermittent rhythmic delta activity with no spiking, were present at 6 hr with return to normal at 24 hr.

Clinical Trials as Topic↗