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Biomedical subjects

B Dixon

Publications and source records attributed to B Dixon.

At least 145 records · Page 8Linked to original sources

Comparison of the Lippes Loop D and tapered Lippes Loop D intrauterine devices.

The tapered Lippes Loop D (LLD) is compared to the standard LLD to evaluate efficacy and termination events. The tapered device was designed with the intention of lowering the expulsion rate below the rate for women with standard Lippes Loops. The two devices were randomly assigned to 989 women in two studies. Expulsion rates for the tapered device were lower at six months (p less than 0.10) and at 12 months (p less than 0.05). When the women were divided into groups by uterine measurement, the differences continued to be significant for women with larger uteri but not for those with smaller uteri. Comparison of other pertinent event rates showed no significant differences. Analysis of the data indicates that the tapered LLD represents an improvement in expulsion rates over the standard LLD.

Female↗

Ultrastructure and electron-probe x-ray analysis of the pigment in melanosis duodeni.

A patient with peptic ulceration developed melanosis duodeni, which was studied by light microscopy, histochemistry, electron microscopy and electron-probe x-ray analysis. Our studies show that the pigment in melanosis duodeni resides in the lysosomes of macrophages in the lamina propria. The pigment is not melanin or a melanin-like compound as has been claimed by previous workers. On the basis of electron-probe x-ray analytical findings we have concluded that the pigment is essentially FeS. On the basis of the history of this patient and cases reported in the literature we think that the Fe in this pigment is derived from haemorrhage in the gastrointestinal tract. We also found small amounts of Ca, K, Al, Mg, Si, and Ag. It would appear that Al, Mg and Si were probably derived from the biological milieu and/or other drugs and/or food and/or specimen contamination.

Cytoplasmic Granules↗

Grub.

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Child↗

But I was there!

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Age Factors↗

A word of warning.

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Product Labeling↗

Corticopontine visual projections in macaque monkeys.

These experiments were designed to study the projections to the pons from visual and visual association cortex of monkeys by degeneration staining and horseradish peroxidase (HRP) methods. When lesions were made in these cortical visual areas, degenerated fibers were found in the rostral dorsolateral area of the pontine nuclei. When HRP was injected among visually responsive cells in this region of the pons, layer V cortical pyramidal cells were labeled. These labeled cells were concentrated most heavily on both banks of the superior temporal and intraparietal fissures, and on the rostral bank of the parieto-occipital fissure. The efferent targets and receptive field properties of these cortical regions are consistent with their possible role in visual guidance of movement.

Animals↗

Vaccination of chicks against Plasmodium gallinaceum by erythrocytic and exoerythrocytic parasites attenuated by gamma irradiation.

Plasmodium gallinaceum-infected blood which received up to 24 krad during exposure to gamma-rays from a cobalt-60 source produced infections of normal course and duration when injected into chickens. The prepatent period advanced with increasing exposure of infected blood to radiation, suggesting some degree of attenuation. At 26, 28 and 30 krad, the infections were transient and the parasites were morphologically abnormal. It is thought that the amount of radiation required to render the parasites non-viable is about 45 krad for an inoculum of 10(6) parasites. There is evidence that exoerythrocytic stages may be more susceptible to gamma-rays than are blood parasites. Chickens were inoculated three times, over a period of four weeks, with vaccines prepared from gamma-irradiated infected blood and brain tissue. Half the birds which had been inoculated with attenuated parasitized blood exhibited mild infections during vaccination, and they were the only birds to show at challenge immunity to both homologous blood and exoerythrocytic parasites.

Animals↗