[Methodology of regional chemotherapy of the lung].
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Biomedical subjects
Publications and source records attributed to B D Zislin.
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Blood clotting system has been studied over the course of pregnancy. The detected close correlations between hemostasiograms and labor hemorrhages suggested the possibility of predicting hemorrhagic complications. Based on informative signs, the authors formulate the rules for predicting hemorrhagic complications of labor starting from the first trimester and define the algorithm of monitoring the hemostasis system. Application of this system helped decrease the incidence of labor hemorrhages by half by means of appropriate preventive therapy.
Mechanisms of development of multiple organ failure (MOF) in gestosis have been studied. Analysis of the findings of examinations of 95 women with gestosis hospitalized in intensive care wards of Institute for Maternity and Neonatality Protection demonstrated that elements of the systemic inflammatory response syndrome (SIRS) underlie the development of MOF syndrome in gestosis, which can be diagnosed starting from early terms of gestation.
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Pregnants in the third trimester with medium- and severe gestosis were divided into 3 groups according to types of maternal and fetal hemodynamics: 1) controls (n = 58 pts); 2) eukinetic type (n = 54 pts); and 3) hypokinetic type (n = 55 pts). Each group was subdivided into 3 subgroups according to administered types of anesthesia for cesarean section (epidural, spinal, and general). Central hemodynamics of the mother, fetus, and fetoplacental complex was studied. Use of different anesthesias in woman with normal pregnancy did not affect the hemodynamics, and therefore any type of anesthesia can be used in cesarean section. In pregnants with gestosis, the eukinetic hemodynamic and compensated or subcompensated placental insufficiency the optimal anesthesia was epidural and spinal. For pregnant with hypokinetic circulation and subcompensated or decompensated placental insufficiency epidural anesthesia is preferable.
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The history of the auscultation method of arterial pressure (AP) measurement dates back to more than century ago. Nevertheless, the problem of the accuracy of measurement is still on the agenda. Standards of the accuracy of measurements and data processing are subjects of regular revision and update. The accuracy and reliability of AP monitoring in complex clinical cases are competitive advantages important for manufacturers of medical monitors. A new Triton ElectronicS module for AP measurements based on original technology and results of its testing are considered in this work. An original algorithm of the module operation provides an opportunity for more accurate and convenient monitoring, particularly in case of disordered hemodynamics.
Progress in information technologies significantly modified conventional approaches to monitors of vitally important parameters of patient. Monitoring systems are not autonomous devices anymore. Instead of that, these systems provide access to electronic case histories, automated monitoring of drug therapy, and many other important functions. Cordless radio and infrared interfaces provide a physical basis of implementation of new user functions. New trends in the development of central monitoring networks (CMN) available from various manufacturers are reviewed in this work. These trends are illustrated taking the Triton ElectronicS CardioNet CMN as an example.
Presently, pulsoximeters are very common devices used in every surgical operation. Unique properties of pulsoximeter (safety, accuracy, and efficiency) enable physician to monitor oxygen-transporting function of blood, which is a vitally important function of human body. The history of pulsoximetry dates back to several generations ago, researchers of many countries being involved in the invention of this device. The idea of pulsoximetry has been updated at each stage of technological progress. The history of pulsoximetry illustrates progressively increasing importance of spectrophotometric method in medicine and its perspectives for the future.
The problem of inhalation gas mixture conditioning, an important problem of technological implementation of high-frequency jet apparatuses for mechanical lung ventilation (MLV), is discussed. Methods of heating and humidification of inhaled gas mixture are considered along with conventional methods used in anesthetic MLV apparatuses.
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Basic systemic hemodynamic parameters were compared during intravenous anesthesia with calypsol (ketamine) and diazepam, promedol and diazepam, fentanyl and diazepam, fentanyl and sombrevin in 120 patients operated on the lungs with conventional and high-frequency jet ventilation. The studies have shown that in conventional controlled lung ventilation there were no distinctions in hemodynamic parameters depending on the type of the anesthesia. In high-frequency jet ventilation, specific hemodynamic effects of calypsol were observed. Unlike other anesthetics, calypsol administration is associated with elevated central venous pressure, increased cardiac output and enhanced left ventricular work, which can be accounted for by higher venous return.
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