NIMH/MacArthur Foundation workshop report. Treatment of depression in late life.
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Biomedical subjects
Publications and source records attributed to B D Lebowitz.
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Raven's Colored Progressive Matrices Test (RCPM) was administered to 894 normal healthy adults who were randomly selected in six Italian cities and in the Republic of San Marino. Gender, age, and education significantly influenced overall test performance, and performance on different RCPM subsets. Findings from this large random sample provide demographic corrections to test scores for use in clinical practice.
The National Institutes of Health (NIH) Consensus Development Conference on the Diagnosis and Treatment of Depression in Late Life took place on November 4-6, 1991. The full statement of the Consensus Panel, chaired by Arnold J. Friedhoff, M.D., was published in a Consensus Statement and in the Journal of the American Medical Association. The purpose of this article is to provide a brief overview of the planning for the Consensus Development Conference, with particular emphasis on the questions posed by the National Institute of Mental Health (NIMH) Planning Committee to members of the panel. This is followed by a brief synopsis of the panel's opinions on issues raised by the NIMH Planning Committee, as well as their opinions on the most promising issues for future research in late-life depression. The main purposes of the NIH Consensus Development Conference were first, to translate research findings into guidelines for clinical practice, so far as this is possible, and second, to suggest promising directions for the Nation's research agenda in late-life depression.
The authors present an overview of research questions related to psychopathology in elderly patients. Specific research questions in the areas of organic mental disorders, affective disorders, personality disorders, anxiety disorders, psychotic disorders, and substance abuse are presented. Clinical investigators are encouraged to pursue some of these specific questions in order to facilitate diagnosis and to develop specific effective treatment strategies for psychopathology in older patients.
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This study identified significant sources of variability in the utilization of CMHC services by the elderly. Program and staff specialization were examined as they critically influenced the rate of service utilization as well as the types of services made available. Data from a 1984 national survey of CMHC's were analyzed and statistically significant differences were found in overall utilization, types and amounts of direct and indirect services, and number and types of separate service delivery sites. These results suggest that variability in services utilization may be attributable to programmatic differences between CMHC's and may constitute a significant aspect of services designed to address the special needs of the elderly.
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The organizational dimensions of the shift in aging policy from a services strategy to an income strategy are examined. With data from the first year of a longitudinal study of the impact of the new Supplemental Security Income program in the United States, hypotheses about the local-level effect of federally mandated changes in the relationships between organizations and in the adaptation of focal organization staff are tested. Domain consensus, differential prestige and complementarity of function are identified as important factors in the implementation of change.
Recent research in the quality of life has identified a sense of security as a significant component. Taking its negative, fear, the personal and structural factors associated with fear of walking around one's neighborhood were assessed in a secondary analysis using data from a 1973 representative national sample collected from the National Opinion Research Center. Although the direct effect of age on fear was minimal, clear and significant age differentials on fear were found by income, size of city of residence, and the presence or absence of others in the household.
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OBJECTIVE: A consensus conference on the diagnosis and treatment of Alzheimer disease (AD) and related disorders was organized by the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatrics Society on January 4 and 5, 1997. The target audience was primary care physicians, and the following questions were addressed: (1) How prevalent is AD and what are its risk factors? What is its impact on society? (2) What are the different forms of dementia and how can they be recognized? (3) What constitutes safe and effective treatment for AD? What are the indications and contraindications for specific treatments? (4) What management strategies are available to the primary care practitioner? (5) What are the available medical specialty and community resources? (6) What are the important policy issues and how can policymakers improve access to care for dementia patients? (7) What are the most promising questions for future research? PARTICIPANTS: Consensus panel members and expert presenters were drawn from psychiatry, neurology, geriatrics, primary care, psychology, nursing, social work, occupational therapy, epidemiology, and public health and policy. EVIDENCE: The expert presenters summarized data from the world scientific literature on the questions posed to the panel. CONSENSUS PROCESS: The panelists listened to the experts' presentations, reviewed their background papers, and then provided responses to the questions based on these materials. The panel chairs prepared the initial drafts of the consensus statement, and these drafts were read by all panelists and edited until consensus was reached. CONCLUSIONS: Alzheimer disease is the most common disorder causing cognitive decline in old age and exacts a substantial cost on society. Although the diagnosis of AD is often missed or delayed, it is primarily one of inclusion, not exclusion, and usually can be made using standardized clinical criteria. Most cases can be diagnosed and managed in primary care settings, yet some patients with atypical presentations, severe impairment, or complex comorbidity benefit from specialist referral. Alzheimer disease is progressive and irreversible, but pharmacologic therapies for cognitive impairment and nonpharmacologic and pharmacologic treatments for the behavioral problems associated with dementia can enhance quality of life. Psychotherapeutic intervention with family members is often indicated, as nearly half of all caregivers become depressed. Health care delivery to these patients is fragmented and inadequate, and changes in disease management models are adding stresses to the system. New approaches are needed to ensure patients' access to essential resources, and future research should aim to improve diagnostic and therapeutic effectiveness.