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Biomedical subjects

B D Ferris

Publications and source records attributed to B D Ferris.

26 records · Page 2Linked to original sources

To stitch or not to stitch the fat?

A total of 22 patients having hip replacements were studied to determine biochemically whether or not fat stitches cause fat necrosis. We found that fat necrosis, as measured by the triglyceride concentration of the drainage fluid, occurred in all wounds. The use of a fat stitch did not increase the amount of fat necrosis, but significantly reduced the amount of fluid drained (P less than 0.001; Student's t test). This retention of triglycerides is probably undesirable as they can act as a substrate for prostaglandin synthesis.

Adipose Tissue↗

Coracoid process transfer for acromioclavicular dislocations. A report of 20 cases.

Twenty patients with acromioclavicular dislocations treated by transfer of the coracoid process to the clavicle were reviewed and were compared to a previous study. Surgery was performed for acute dislocations in seven cases and for chronic dislocations in 13 cases. At the follow-up examination (5.6 +/- 3.5 years for acute and 4.0 +/- 3.6 years for chronic dislocations), all patients had some relief of their symptoms. Nine patients had residual aching in the joint, and this was associated with an older age at injury (40 years as opposed to 25 years for chronic dislocations). Complications included superficial wound infections in two patients, transient stiffness of the shoulder in two patients, loss of range of movement in one patient, and subjective weakness in one patient. In general, satisfactory results were achieved in younger patients, but as the results of conservative treatment of these injuries are comparable, the operation is indicated only in patients with symptomatic chronic acromioclavicular dislocations.

Acromioclavicular Joint↗

An unusual presentation of tuberculosis--'injury TB'.

Thirteen patients are presented who developed tuberculosis at the site of injury. They were all immigrants from areas where tuberculosis is endemic. The presence of injury caused a delay in diagnosis and therefore appropriate treatment. In an immigrant with an injury that pursues an unusual or protracted course, tuberculous infection should be considered.

Adolescent↗

Altered organization of non-collagenous bone matrix in osteoporosis.

In osteoporosis it is postulated that while the amount of bone is diminished, the quality of the bone is unaltered. Recently relatively novel methods of analysis have shown that, at the fracture site of osteoporotic subcapital fractures, there is a marked change in the molecular orientation of components of the non-collagenous bone matrix. These procedures, now applied to iliac crest biopsies, confirm earlier findings of altered orientation of the proteoglycans at the subcapital fracture site but show that very similar changes occur even in the iliac crests from patients with both types of osteoporotic proximal femoral fracture. Thus, whereas the amount of these acidic moieties of the non-collagenous bone matrix was unchanged, the molecular orientation was markedly altered, albeit not to the same extent as that found at the fracture site. These results imply that the quality of the bone, as well as the quantity, may be generally affected in osteoporosis.

Adult↗

Hydatid disease of the cervical spine.

Hydatid disease affecting the cervical spine occurred in a 31-year-old man. Because bone grafting is associated with a high failure rate, treatment included filling the excised defect with a high-density polyethylene implant and fusing the cervical spine to stabilize it.

Adult↗