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Biomedical subjects

B Cylwik

Publications and source records attributed to B Cylwik.

At least 73 records · Page 4Linked to original sources
PubMedDate not supplied

[Proliferative activity of glial neoplasms of the brain].

The aim of the study including 89 brain gliomas was to determine their proliferative activity assayed with immunohistochemical methods (PCNA and Ki-67) and with the method of AgNORs, as well as to evaluate the correlation between the proliferative activity and features of histological malignancy. The study reveals that the estimation of PCNA, Ki-67 and AgNORs are effective methods for the determination of the proliferative activity of brain gliomas. Statistically significant differences were noted in the proliferative PCNA, Ki-67 and AgNORs between groups of gliomas with lower and higher malignancy, which indicated a distinct correlation between histological malignancy of the tumours and their proliferative activity. High values of PCNA and Ki-67 (> 40%) and AgNORs (> 15) were found to considerably deteriorate prognosis in brain gliomas.

Adult↗
PubMedDate not supplied

Effect of asparagine and arginine on the repair of isoprenaline-damaged myocardium of rat.

The effect of asparagine and arginine on the repair of isoprenaline-damaged myocardium was studied. In group I (treated with isoprenaline) the rats developed large foci of myocardial damage filled by connective tissue after 14 days. Similar changes were observed in group II (isoprenaline + asparagine). In group III of rats treated with isoprenaline and arginine the number of foci of injury and their size were smaller, and only a few small foci fibrosis were found after 14 days. Arginine seems to protect the rat myocardium from isoprenaline-induced damage. The repair by connective tissue is supplemented by compensatory hypertrophy of muscle fibers.

Animals↗