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Biomedical subjects

B Crosson

Publications and source records attributed to B Crosson.

38 records · Page 3Linked to original sources

Recall of three words after five minutes: its relationship to performance on neuropsychological memory tests.

This paper examines the statistical relationship between a memory screening test (recall of three words after 5 minutes, 3W5M) and an extensive battery of neuropsychological memory tests. Subjects were 142 consecutive referrals for neuropsychological examination and were given 3W5M in addition to measures of memory, language, and intelligence. Performance on 3W5M was categorized as either "impaired" or "unimpaired" in a manner consistent with judgement used in clinical settings. Linear discriminant function analysis was used to predict 3W5M performance from neuropsychological test scores. Results indicated that 3W5M was a relatively good screening measure, but that its sensitivity and utility as a measure of memory was significantly influenced by the nature of the neurological disorder. Significantly higher diagnostic accuracy rates were obtained in patient groups with clinically obvious memory impairment (e.g., dementia, pure amnesia) than in groups with less obvious memory impairment (e.g., closed head injury, psychiatric disorders). Implications for clinical memory testing, and for the relationship between screening and battery approaches to assessment, are discussed.

Journal Article↗

Method for registering brain SPECT and MR images.

We have developed a simple method for locating functional regions of interest on successive SPECT scans obtained at different times and for locating neuroanatomical regions defined with MR on functional images obtained with SPECT. Plastic molds are made for each external auditory meatus and the glabella. A pocket is then made in each mold in which either a 57Co disk (for SPECT) or an identical disk containing CuSO4 solution (for MRI) can be placed. Transaxial tomographic slices are reconstructed with the same slice thickness in the two modalities. The SPECT software rotates both SPECT and MRI reconstructed images so that the three 57Co markers lie in one SPECT reference plane and the three CuSO4 markers lie in one MRI reference plane. Corresponding SPECT and MR images may then be displayed simultaneously to locate chosen regions of interest. The technique was validated by taping test markers to the forehead of 12 subjects; the difference between the positions of the centers of the test markers on SPECT and MR scans was within 1 SPECT acquisition pixel size.

Brain↗