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Biomedical subjects

B Cox

Publications and source records attributed to B Cox.

At least 235 records · Page 13Linked to original sources

A problem-oriented system approach to analysis of treatment outcome.

Data on 90 psychiatric patients' perceptions of the course and outcome of hospitalization were gathered using a problem-oriented system. Patients were interviewed on admission, at discharge, and at two follow-up intervals. Therapists perceptions of patients' problems and their severity were also assessed on patients' admission and at discharge. Although the absolute number of problems reported by patients increased over time, there was a significant decrease over time, there was a significant decrease in the level of distress associated with problems on both patients' and therapists' ratings. The dynamics of this improvement are discussed from the perspectives of both patients and therapists.

Adult↗

Interactions of L-dopa and amantadine in patients with Parkinsonism.

Twenty-seven patients with Parkinson's disease participated in a double-blind crossover trial of L-dopa and amantadine. Each drug was given for six weeks, and six weeks were allowed to elapse between the two periods of treatment. Marked improvement occurred in patients given L-dopa first, whereas no clinical effect was observed in those patients treated first with amantadine. L-dopa was less beneficial to patients who had previously received amantadine, whereas amantadine became effective in patients who had previously taken L-dopa. The effect of pre-treatment with one drug on the therapeutic effectiveness of the other drug is reflected in changes of homovanillic acid levels in the cerebrospinal fluid.

Amantadine↗