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Biomedical subjects

B Court

Publications and source records attributed to B Court.

50 records · Page 3Linked to original sources
PubMedDate not supplied

[Melanoma of the penis: 6 cases].

BACKGROUND: Melanomas of the penis are rare tumors of poor prognosis. METHODS: Six cases of melanoma of the penis, followed between 1975 and 2002, were retrospectively reviewed. We collected the data on epidemiological, clinical and pathologic factors, treatment and follow-up. RESULTS: The mean age was 44 years. The time to diagnosis was 2 years. Two patients had general predisposing factors for melanoma, and 3 patients local predisposing factors. Two patients had partial penectomy and 4 patients had conservative excision. One patient had local recurrence, and another had metastatic course resulting in death. Five patients out of 6 were alive and disease free at time of the study, with a 24 month follow-up. DISCUSSION: The identified risk factors for the development of penile melanoma are melanosis and pre-existing nevus. Delayed diagnosis explains the usually bad prognosis. Classical surgical treatment used to be radical, but recently, conservative surgery has been proposed. For an early diagnosis, genital melanosis requires surgical excision, when technically feasible, and any atypical lesion of the penis should be submitted to a biopsy.

Adolescent↗
PubMedDate not supplied

[Action to be taken in traumatic rupture of the urethra in boys (4 cases) (author's transl)].

On the occasion of four cases, the authors studied the problems posed by traumatic rupture of the urethra in boys. They draw a very clear distinction between fresh rupture where the urethral lesions are only one of the elements of multiple trauma. The clinical picture and the I.V.P. form the basis for the diagnosis, and the indwelling catheter when it can be placed in position remains a valid mode of treatment. At the stage where complications have arisen, a clinical as well as a radiological check-up is indispensable before taking any decision. If action must be taken, suture-resection seems to be the best solution.

Adolescent↗
PubMedDate not supplied

Monitoring and treatment of minimal residual cancer of the prostate.

In manifest prostatic carcinoma, partial and complete remissions are obtained in 14-44% of patients as judged by different sets of criteria, but in up to 61% as judged by a decrease in prostatic acid phosphatase. Moreover, this decrease is poorly correlated to that of prostatic size. Prostatic acid phosphatase is therefore considered to be a relatively non-specific tumor marker. A complete remission, i.e. a stage of minimal residual disease, is obtained in about 25% of the patients. Continued endocrine treatment involves the risk of a flare-up of the disease, which is probably small. Additionally, in minimal residual disease, prolonged maintenance treatment requires minimization of side effects. D-Trp-6-LH-RH appears to lead to less gynecomastia and thromboembolism than some other forms of adjuvant therapy.

Adenocarcinoma↗
PubMedDate not supplied

The RCP stroke audit package in practice.

This paper describes the use of the Royal College of Physicians 'stroke audit package' in an audit of the care of 156 patients. Recording of history and management compared favourably with that recorded on the RCP database. For a number of items, recording was significantly improved when a locally developed 'checklist', based on the RCP standards, was utilised by trainee medical staff. Benefits of the audit package, and proposed changes in practice, are briefly outlined.

Cerebrovascular Disorders↗