[D-penicillamine in the treatment of rheumatoid arthritis].
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Biomedical subjects
Publications and source records attributed to B Colombo.
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In the second part of the Authors work, they report the results obtained in the treatment of 85 female children with recurrent non malformative urinary tract infections. The first group of 15 female children had been treated with phenoxybenzamine and urinary chemyotherapycs with little satisfaction. The other two groups, both of which consisted of 35 children, one group was treated with only chemyotherapycs and the other with chemyotherapycs associated to oxybutynin chloride. The best results were obtained in the last group regarding the improvement of the symptoms and earlier and higher incidence of sterilization of the urine. At the same time in this group the maximum cystometric capacity and vesical compliance were brought back to normal and the detrusorial instability disappeared.
Acute hydrops of the gallbladder is described in a patient who had mucocutaneous lymph node syndrome. Diagnosis was readily made with gray-scale ultrasound. Serial sonograms were obtained to follow the resolution of the hydrops once supportive medical therapy was started. The role of surgery in acute hydrops of the gallbladder is for complications of the hydrops and not for distension alone.
The results of histological, histochemical and electron microscopic study of the muscular involvement in eight patients with Ankylosing Spondylitis (AS) are described. Muscle tissue from all these patients showed gross abnormalities of the sacrospinalis muscle, which had a 'targetoid core' appearance common to several myopathic and neurological diseases. In our opinion, there is always constant and early involvement of this muscle in AS. Several factors associated with the disease (chronic inflammation, multiple enthesopathies, muscle stiffness and bone lesions) could be responsible for this not fully understood aspect of AS. They may lead to a non specific damage of the nervous and/or muscular components of the spine in these patients.
The authors report a typical case of hyperthyroidism with alopecia in a 5 years old female child with family precedents. We punctualize the present etiopathogenetic theory and the therapeutical possibilities.