[Polydysplastic incontinentia pigmenti: report of two cases].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to B Christol.
Explore the source record for details and available documents.
Vertical striated sand-papered twenty-nail dystrophy, an entity observed in both children and adults, is suggestive of an expression of alopecia areata. When the vertical striated sand-papered effect is not uniformly distributed over the full surface of the nail plates the disorder may be caused by lichen planus.
Lamprene (Clofazimine) was administered over a period of three months, at a dose of 100 mg to 200 mg per day, to six patients with chronic lupus erythematosus. Remission was observed in these six cases, without any side-effect.
Explore the source record for details and available documents.
The acquired fibro-keratoma is a benign fibro-epithelial tumor of acquired nature. I was set apart as a distinct entity in 1968 by Bart et al. who named it "acquired digital fibro-keratoma". It is predominantly, although not exclusively, located on the fingers and toes, near the phalangeal joints. The authors report 8 personal cases and make a short general review of the disease. The lesion is slightly prominent, well defined and surrounded by a hyperkeratotic collar. It protrudes on the surface of the skin much like a hernia. Histologically, it is a dermo-epidermal tumor. There is a proliferation of connective tissue under the papillomatous, hyperacanthotic and orthokeratotic epidermis. The mature collagen bundles, voluminous fibroblasts and numerous enlarged capillaries are parallel to the vertical axis of the tumor. The acquired fibrokeratoma must be differentiated from other cutaneous tumors, particularly fibromas and Koënen's tumors. The etiology is unknown. However, it was found in some cases that a trauma had contributed to the development of the tumor. The only possible treatment is surgical excision.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The authors have collected 6 cases (one personal case and 5 cases from the literature) of hyperkeratosis punctata of the palmar creases, an affection which seems to be a new type of keratosis punctata. It is characterized by the development of small horny plugs in small cup-like depressions which are electively and exclusively found in the palmar flexion creases of the fingers. Histological examination shows a plug-like hyperkeratosis penetrating, more or less deeply, the depressed, funnel-like Malpighi's mucous layer which sometimes consists of one layer of cells. This affection might be compared to Kyrle's disease (and the hyperkeratotic plugs of mechanical origin). The histological evidence of non-rupture of the dermis by the horny plugs may not be considered as a sufficient factor of differentiation: however, other clinical criteria differentiate these various affections. In the absence of a known etiology we must conclude that this type of keratosis punctata confined to the palmar creases is an autonomous disease.
We saw three patients with inflammatory linear verrucose epidermal nevus (ILVEN). The purpose of this study is to better delineate the histopathologic features of this type of nevus. In fact, in all three cases very particular, specific histologic lesions have been noted that permit us to better distinguish this recently outlined entity. The histologic features were depressed, cup-like areas of hyper-granulosis with overlying orthokeratotic hyperkeratosis, alternating (with sharp dermacation) with raised, level areas of agranulosis with overlying parakeratotic hyperkeratosis.
The authors present a case of dermatomyositis with generalised spinulosis of pilose pityriasis rubra (lichen ruber acuminatus) type, giving a highly characteristic appearance of linear verruciform spinulosis of the back of the hands. They describe the histological lesions and feel that this spinulosis is probably due to marked degenerative smooth muscle myositis of the erector pili muscles. They recall the earlier cases of O'Leary and Christianson and above all those of Wong. The case reported is the first in a child.
The following aspects of the classic geographic tongue are discussed: clinical polymorphism with the appearance of annulus migrans, histological appearacne of the spongiform pustule, frequent association with pustular psoriasis and related diseases, and its relationship to psoriasis buccalis. Two cases of geographic lip are described in which annulus migrans was present. In one case, the geographic lip was associated with a plicated lip, a labial form of plicated tongue.
Explore the source record for details and available documents.
In a typical case of geographical lip, the authors discovered the presence of parallel vertical grooves on the mucosal side of the lips and believe these are similar to those observed in folded tongue. They concluded that there is a possible association "geographical lip and folded lip", comparable with the association "geographical tongue and folded tongue". They then carried out a histological study and proposed an etiopathogenic explanation for the folds in the lip in comparison with the fissures of the tongue, dysembryoplasia due to heterotopy of the gustatory or lymphopoietic grooves.
A case of annulus migrans associated with a Pustular Bacterid of Andrews is presented by the authors. The relationship between annulus migrans and psoriasis is discussed.
Explore the source record for details and available documents.
Explore the source record for details and available documents.