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Biomedical subjects

B Carstocea

Publications and source records attributed to B Carstocea.

8 recordsLinked to original sources
PubMed2001

[Difficulties in cataract surgery of patient with old glaucoma].

Cataract surgery of glaucoma patients treated with Pilocarpine several years, with a small and miotic pupil, with synechiae is an important problem of management. The self-retaining flexible iris retractor is a microsurgical innovation that allows adequate enlargement of the pupil without iris incision. Each retractor is inserted through a separate self-sealing beveled incision made as far posteriorly in the cornea as possible. The retractors are spaced 90 degree apart and can easily be removed following implant insertion. The conclusion is that if we obtain an adequate enlargement of the pupil we can choose any cataract surgery technique, even phacoemulsification or EEC.

Cataract↗
PubMed1999

Topical netilmicin compared with tobramycin in the treatment of external ocular infection.

In a pilot double-blind, randomized, prospective controlled study the effectiveness and safety of 0.3% netilmicin ophthalmic solution were compared with those of 0.3% tobramycin in treating external bacterial ocular infections in 45 eligible patients. The treatment with both study medications resulted in a significant (p < 0.001, Wilcoxon test) reduction in the mean cumulative score of the signs and symptoms. However, no statistically significant differences were observed between the two groups. The clinical improvement rate was almost complete with either antibiotics. There was a statistically positive trend in the netilmicin group with regard to the microbiological improvement that was achieved in (87% of the netilmicin patients) compared with 77% of the tobramycin patients (77%). Antibiotic sensitivity revealed that 84% of the organisms isolated were sensitive to netilmicin whereas only 64% of them were sensitive to tobramycin. Only minor adverse events occurred in patients treated with either netilmicin or tobramycin. In conclusion, this study demonstrates that netilmicin is a promising new antibiotic for treating external ocular infections.

Administration, Topical↗
PubMed1999

[Difficulties in the diagnosis of glaucoma; the therapeutic implications].

The glaucomatous disease has, the most of time, an insidious beginning; the diagnosis is occasioned by some refraction problems or by a systematic ophthalmological examination or a request coming from another physician. As a consequence, the diagnosis of glaucoma is not always very easy thing, because, in the early stages, the diagnostic criteria rises special problems. Under these conditions, the therapeutical attitude will be differentiated from a case to another. After these general considerations, the authors will discuss some clinical cases, knowing that the diagnosis and the initiation of treatment will give rise to some contradictory discussions.

Adult↗
PubMedDate not supplied

[The use of prostaglandin compounds in treating glaucoma].

The theoretical part of this paper presents the mechanism of the IOP lowering effect using these drugs, the indications of treatment and the main side effects. The second part consist of the experimental study made on rabbits, using the izopropilic ester of (+)Cloprostenol as an hypotensive agent. We have registered the IOP values and the main side effect--conjunctival hyperemia. The third part consist of the clinical study, made on a test lot of 23 patients. We have used the same substance and in the experimental study, as a unique treatment or in association with a beta-blocker or a pilocarpine derivative. The following-up has implied: the IOP, the ophthalmoscopic appearance of the optic disc, the visual field, the visual acuity and the main side effects. In the end, we have formulated the conclusions of these studies.

Adrenergic beta-Antagonists↗