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Biomedical subjects

B Cardo

Publications and source records attributed to B Cardo.

At least 55 records · Page 3Linked to original sources

[Rhythmic slow waves and multi-unit activity during sleep-waking cycle in the rat ventral tegmentum].

1. Multi-unit activity (MUA) was recorded together with gross activity in different structures during various states of sleep in 43 rats. The records were made by means of telemetry from lateral hypothalamus, nucleus ruber, formatio reticularis, dorsal hippocampus and the ventral mesencephalic tegmentum (VMT) surrounding the nucleus interpeduncularis. 2. The records during paradoxical sleep showed slow rhythmic theta waves located in the VMT and the dorsal hippocampus. In these two structures the MUA was mainly organized in periodic patterns of discharges. In the other structures a continuous increment of the basic level of discharge was superimposed on the periodic patterns. 3. The similarity of the hippocampal and VMT records strengthens the hypothesis that the VMT region has anatomical and functional connections with the limbic system.

Action Potentials↗

Rhythmic slow wave activity recorded in the ventral mesencephalic tegmentum in the rat.

1. Slow rhythmic theata-type waves were recorded in the sub-interpeduncular ventral mesencephalic tegmentum (VMT) in the rat. This region is one of the parts of the "limbic midbrain area". These waves are recorded during certain attentive waking states, during the execution of voluntary movements and during paradoxical sleep. 2. These rhythmic VMT waves seem to be of the same nature as the theta rhythm recorded in the limbic structures. A lesion of the septum suppresses the slow rhythmic waves at the mesencephalic level as well as at the telencephalic level. 3. Although we have now shown that the mesencephalic and telencephalic slow rhythmic waves have the same pacemaker, the pathways which transmit the theta rhythm to the VMT are not well known. However, it is reasonable to suppose that the fibres of the post-commissural fornix are involved in this transmission.

Animals↗