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Biomedical subjects

B C White

Publications and source records attributed to B C White.

84 records · Page 5Linked to original sources
PubMed1976

Pulseless idioventricular rhythm during CPR: an indication for massive intravenous bolus glucocorticoids.

Five consecutive patients were initially resuscitated successfully from pulseless idioventricular rhythm with the use of 100 mg of dexamethazone administered by intravenous push after all conventional modes of management had failed. In this small series, two of the five patients are long-term survivors and the deaths of the other three patients are attributable to advanced underlying pathology. The possible mechanisms of action of the glucocorticoids are not conclusively known. There is a need for detailed laboratory study of Purkinje conduction and single-cell depolarization and mechanical patterns, under controlled settings approximating the clinical conditions.

Adult↗
PubMedDate not supplied

Why nurses must actively participate in the debate on assisted suicide: a symposium.

This article argues that nursing must undertake further careful study of assisted suicide. Nursing must determine the relationship of assisted suicide to its core values as an important condition for making beneficent, patient-centered clinical decisions as well as for participating in discussions that establish public policies and professional practice standards.

Decision Making↗
PubMedDate not supplied

The moral appeal of assisted suicide in end-of-life decisions.

This article identifies conceptual distinctions, e.g., killing, letting die, causing, refraining from causing, and moral principles, eg, autonomy, beneficence, utility, and their implications for the debate on assisted suicide.

Attitude to Death↗
PubMedDate not supplied

Assisted suicide and nursing: possibly compatible?

This article argues that the American Nurses Association's (ANA) prohibition of nurse-assisted suicide is misguided. The ANA's reasons for this policy do not provide the necessary conceptual or empirical support for the prohibition. In fact, arguments appear to lead to support for nurse-assisted suicide: (1) because the claim that death is always harmful may be false, the obligation to "do no harm" does not necessarily preclude assisted suicide (AS); (2) currently we have no evidence that AS would erode public trust in nurses; (3) AS may be compatible with the professional integrity of nursing, particularly the commitments to respecting autonomy, promoting patient welfare, and providing compassionate care; (4) nursing's participation would constrain, rather than contribute to, the potential for abuse to vulnerable patient populations; and (5) the professional has a responsibility to either embrace the public's increasing support of aid in dying or determine why AS is morally indefensible and educate the public.

American Nurses' Association↗
PubMedDate not supplied

The effect of resuscitation technique and pre-arrest state of oxygenation on blood-gas values during cardiopulmonary resuscitation in dogs.

Large mongrel dogs were anesthetized, instrumented, and subjected to electrically induced ventricular fibrillation after breathing either 100% oxygen (O2) or 10% O2 and 90% nitrogen for 10 minutes before arrest. Four minutes after arrest, open chest cardiopulmonary resuscitation (CPR) or intermittent abdominal compression closed chest CPR was initiated and continued for 20 minutes, at which time defibrillation was attempted. Central arterial and mixed venous blood samples were collected serially for the measurement of pH, carbon dioxide partial pressure (PCO2), and O2 partial pressure (PO2), and calculation of bicarbonate concentration and base excess. Mixed venous blood was collected serially for the measurement of lactate concentration. Hemodynamically variable resuscitation techniques and pre-arrest hypoxia or hyperoxia did not significantly influence blood-gas values during CPR. Mixed venous lactate concentrations after 20 minutes of CPR were significantly higher when hypoxia preceded the arrest and when intermittent abdominal compression closed chest CPR was used for resuscitation. Mixed venous PCO2 was significantly higher than arterial PCO2 in all dogs during CPR but was not significantly different before arrest.

Animals↗
PubMedDate not supplied

Ethical issues surrounding informed consent. Part II. Components of a morally valid consent and conditions that impair its validity.

To be valid, a consent must be given by a person who has received all relevant information, is competent, has not been coerced into agreement or refusal, and is not emotionally overwhelmed. Persons who have received incomplete information, are incompetent, have been coerced, or are psychodynamically overcome cannot give valid consent or refusal. HCPs who accept consents or refusals from such patients do not act in accordance with the ethical foundations and goals the practice was designed to promote. Nursing plays a crucial role in assuring the validity of informed consent/refusal. This role will be examined in Part III of this series.

Decision Making↗