Biomedical subjects
B C Loffeld
Publications and source records attributed to B C Loffeld.
The gastrointestinal tract in pernicious anemia.
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Campylobacter-like organisms in Meckel's diverticulum?
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Retrospective study of Campylobacter-like organisms in patients undergoing partial gastrectomy.
One hundred and five stoma biopsy specimens and 108 corpus biopsy specimens from 108 patients who had undergone a partial gastrectomy because of peptic ulcer disease were examined retrospectively for the presence of Campylobacter-like organisms and gastritis. In the corpus biopsy specimens Campylobacter-associated gastritis was found in 55 (71%) of the cases and in 42 (48%) of the stoma biopsy specimens. It is concluded that Campylobacter-like organisms have a role in gastritis after partial gastrectomy, although this role is more prominent in the corpus region. The role of Campylobacter pylori in peptic ulcer disease is not clinically important.
Fungal colonization of gastric ulcers.
Retrospectively, samples from 337 newly diagnosed gastric ulcers were studied for the prevalence of fungus using a periodic-acid Schiff-diastase stain. In 64 (19%) gastric ulcers, fungal material was found in the ulcer base. There was no difference in prevalence of fungi between benign gastric ulcers and ulcerating gastric carcinomas. The "fungal" ulcers tended to be larger in diameter and are more often suspected to be malignant than "normal" gastric ulcers. Since no tissue invasion was found and healing tendency after therapy seemed not to be delayed, we conclude that fungus in gastric ulcer is probably a secondary phenomenon, and has little clinical significance.