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Biomedical subjects

B C Ling

Publications and source records attributed to B C Ling.

8 recordsLinked to original sources

Cecal intubation model in the rat that facilitates selective in vivo study of colonic epithelial biology: preliminary report.

PURPOSE: A free-living animal model with ready and repetitive access to selected regions of the large bowel and with minimally altered bowel anatomy and physiology would facilitate the in vivo study of luminal factors on the colonic mucosa in a steady-state environment. This study describes a novel model of large-bowel intubation in the rat. METHOD: Four Sprague-Dawley rats (240-260 g) had laparotomy and intubation of the distal colon and the cecum via a cecotomy with the use of two small tubes with restraints and transmural anchors. The tubes were tunneled and anchored to the back for infusion of fluid directly into the colon. Tube positions were studied when the animals were killed. Animals were fed on either a 10 percent fiber diet or a fiber-free diet. Stathmokinetic assessment of the distal colon was performed after one week of infusion with phosphate-buffered saline and sodium n-butyrate. RESULTS: The technique produced an easy access without affecting the weight gain of the animals after recovery. Tube positions were accurate after three weeks at the time the animals were killed. Infusions of phosphate-buffered saline and n-butyrate were well tolerated. n-Butyrate infusions twice daily for a week reversed the atrophy in the colonic mucosa induced by dietary fiber deprivation. CONCLUSION: An in vivo large-bowel intubation model permitting selective delivery of luminal factors provides an effective option for the study of colonic mucosal biology.

Animals

Computer-printer denture microlabeling system.

This procedure is easy to use and is cost-effective because it uses equipment that exist in any office or institution. The material used, transparency film for use with plain paper copier, is less expensive than either photographic slide film or normal slide films. Moreover, the transparency sheet can be used again for photocopying until the sheet is fully used up. There is no added cost of development of film, or is it necessary to wait for the whole roll of film to be used before the label can be retrieved and used. The background of the label is clear and only the black images of the characters of the label can be clearly seen. The effect of the transparency film, photocopy ink, and adhesive glue is not known. But no adverse effects have been noted. Microlabels have advantages over conventional labels with characters in font size 8 to 12, because more information, such as the full name of the patient, sex, country of origin, and national identification number can be incorporated. With more detailed information, quick identification of a deceased person can be made. Microlabels with a clear background will have minimal esthetic impact on the patient. The disadvantages of the technique is that it may not withstand a fire. In situations where the deceased body is badly burned, the denture and its identification strip may be burned, too. However, this risk can be minimized by placing the strip in the most posterior part of the denture-palatal in the maxillary denture and distal lingual in the mandibular denture. For testing of durability, dentures with the labels were placed in water for up to 4 months. The labels showed no sign of fading or deterioration.

Copying Processes

A new concept in denture design for patients with few remaining teeth: case reports.

This article presents an alternative to the conventional swing-lock de sign of removable partial denture construction. It incorporates the principles of sectional dentures as well as the swing-lock concept and overcomes some of the limitations of conventional swing-lock dentures. I-bar struts and stainless steel keepers form part of the first section of the denture. The second part of the denture consists of the denture base with the artificial teeth and magnetic retention units. This system has been used successfully in a number of patients whose situations were suitable for the conventional swing-lock design.

Aged

Cleansing and surface modifying agents on implants: fixation and related aspects of aesthetics.

With the prognosis of dental implant replacement of missing teeth becoming better each year, practitioners are focusing their attention on the aesthetic aspects of implantology. However, improvement in aesthetics is only possible with the improvement in implant technology, surgical techniques and prosthodontic procedures. This study aimed at evaluating the effects of various physical and chemical agents on the implant surface; with the view of obtaining increased surface area and biocompatibility. The study found that the treatment of air-aluminum oxide blasted implants using a mixture of 30% HNO3-5% HF acids produced a surface which meets the consideration of aesthetics for implants placed in the anterior maxillary region.

Air