Mechanism of complement binding by the red cell in rheumatoid arthritis.
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Biomedical subjects
Publications and source records attributed to B C Gilliland.
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Three patients with rheumatoid arthritis and abundant circulating intermediate complexes were studied. Two of these patients presented with the hyperviscosity syndrome. All 3 patients had markedly elevated plasma and blood viscosity, and the intermediate complexes were thought to be responsible for the increased viscosity. Studies on the isolated intermediate complexes revealed that they were formed by self-association of IgG-rheumatoid factors.