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Biomedical subjects

B C Easterday

Publications and source records attributed to B C Easterday.

At least 73 records · Page 4Linked to original sources
PubMed1968

Experimental bluetongue disease in white-tailed deer.

Nine white-tailed deer and six sheep were experimentally exposed to the California BTV-8 strain of bluetongue virus. The infections were fatal for seven of the nine deer. An additional deer died from exposure to an isolate of bluetongue virus from bighorn sheep. Clinical signs and lesions of bluetongue in deer were described. The incubation period, signs and lesions of bluetongue and epizootic hemorrhagic disease of deer appear to be similar. Virus isolations were made from the blood and a variety of tissues of exposed deer and identified as bluetongue virus. Neutralizing antibodies were detected in all of the convalescent sera.

Animals↗
PubMed1967

Serological studies of influenza in animals.

Reports have been published on the detection of antibodies in animals, including birds, to human influenza viruses. The work reported in this paper was undertaken in an effort to establish an effective method for differentiating specific antibody from non-specific antibody-like substances that occur naturally in serum.The primary antibody response of experimental animals exposed to influenza virus was readily differentiable from the secondary response following challenge of the animals with homologous viral antigen.Field challenge of cattle and sheep resulted in primary responses only, suggesting the non-antibody nature of inhibitor substances present in their sera prior to challenge.Challenge of swine and turkeys that had previously been involved in outbreaks of influenza resulted in secondary responses differentiable from the response of control swine and turkeys similarly challenged.The differentiation of non-specific substances from specific antibody by the challenge method used may help to clarify the role of animals in the epidemiology of human influenza.

Animals↗
PubMedDate not supplied

Kidney lesions associated with mortality in chickens inoculated with waterfowl influenza viruses.

Seventy-six type A influenza viruses recovered from waterfowl in Wisconsin, California, South Dakota, Florida, Texas, Alabama, and Nebraska were tested for virulence in chickens. The challenge to chickens was intravenous inoculation of first-, second-, or third-egg-passage virus. Each of the virus strains was tested separately in three or four chickens. Eighteen of the 76 viruses caused the death of one or more chickens following inoculation. Postmortem lesions were similar in all dead birds. In decreasing order of frequency, gross lesions included: swollen kidneys evident as accentuated lobular patterns, urates in the pericardial sac, and urates on the surface of the liver. Microscopic lesions present in kidneys were consistent with visceral gout. Mortality was associated with inoculations having higher concentrations of infectious virus. These results indicate that the influenza A viruses circulating in duck populations may include strains potentially pathogenic for chickens.

Animals↗