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Biomedical subjects

B Bryant

Publications and source records attributed to B Bryant.

10 recordsLinked to original sources

Cardiac failure: symptoms and functional status.

The associations between exercise capacity, symptoms and specific aspects of quality of life were examined in subjects participating in a trial of the treatment of heart failure. Patients were assessed on entry and after three months treatment. The principle symptoms were fatigue, breathlessness and chest pain. These limited the extent and speed of physical activities, restricted social, leisure and family life and were associated with emotional distress. There were associations between baseline exercise capacity and measures of quality of life. Change in exercise capacity during three months treatment was correlated with changes in measures of symptoms, limitation of activity and quality of life. The findings confirm the value of change in exercise capacity as a measure of functional status and suggest that it should be supported by a limited number of specific measures of quality of life.

Activities of Daily Living

Stenting tips.

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Humans

Quality of life in non-insulin-dependent diabetes and a comparison with insulin-dependent diabetes.

The reported effects of diabetes on quality of life have been assessed in two groups of attenders at out-patient clinics: 1. One hundred and twenty-one non-insulin-dependent diabetic patients randomly allocated to diet, tablet or ultralente insulin therapy; 2. Fifty-seven patients with insulin-dependent diabetes consecutively attending an out-patient clinic. The overall picture for those with non-insulin-dependent diabetes was of relatively little disruption to most areas of life, but 27% reported considerable loss of enjoyment and reduction in social life. High fasting plasma glucose was significantly associated with fatigue and leisure difficulties. The type of therapy, tablet, diet or insulin, made little difference to psychological, social or attitude variables. Those with insulin dependent diabetes showed similar psychological morbidity, but described a rather different pattern of social consequences with more effects on work and less on leisure.

Activities of Daily Living

Exercise capacity and quality of life in the treatment of heart failure.

In a double-blind study comparing two active treatments (digoxin and xamoterol) and placebo in patients with heart failure, improvements in exercise capacity and quality of life were observed in all three groups, with no significant differences. The substantial benefits seen in the placebo group were probably the result of increased attention from the medical and research staff and suggest the therapeutic value of special heart failure clinics. The relationship between exercise and symptomatic/functional status has been unclear. We developed quantitative measures of quality-of-life variables and examined their relationship with exercise capacity. There were significant relationships between change in exercise duration and changes in breathlessness, tiredness, chest pain, walking difficulty, rate of walking, difficulty with daily tasks, speed of daily tasks, mood, and sleeping. This study confirms the validity of measuring change in exercise capacity and demonstrates that specific measurements of quality of life make an important contribution to the evaluation of the treatment of heart failure.

Adult

Prediction of outcome after coronary artery surgery.

Coronary artery surgery is usually successful in relieving angina but benefits for quality of everyday life are sometimes disappointing. Generalized linear inter-active modelling (GLIM) was used to examine pre-operation predictions of psychological and social outcome 3 and 12 months after coronary artery surgery. The study identified predictors of return to work (social class, previous employment status), psychiatric outcome (pre-operation mental state) and social adjustment (pre-operation mental state, age, social class). Although our analysis of potential predictors of 1 yr outcome at 3 months after surgery was less detailed, early convalescence is likely to be the best time for clinical identification of those at risk of poor long term outcome. The findings have implications for selection and preparation for surgery and identification of those who might benefit from extra rehabilitation.

Age Factors

Quality of life after coronary artery surgery.

Seventy-nine men were assessed using standard interview procedures before and at three and 12 months after coronary artery surgery. At one year, the majority reported relief of angina and reduced difficulty in performing everyday activities, but there was considerable individual variation in changes in quality of life. Overall, there were improvements in mental state, leisure activity, satisfaction and family life, but few benefits for work and sexual relations. For a fifth of patients global quality of life was no better or was worse than before surgery and this poor outcome was not closely related to physical state. Patients who described psychological symptoms or had a 'passive' approach to their illness before operation were less likely to have a good outcome. It is probable that the benefits of surgery could be substantially increased by provision of better facilities including simple individually planned preparation and rehabilitation. The study demonstrates that specific interview based ratings can be used to quantify changes in those aspects of quality of life which are most important to patients and their families.

Angina Pectoris

A survey of social inadequacy among psychiatric outpatients.

An investigation into the extent and nature of social inadequacy among outpatients diagnosed as neuroses and personality disorders was undertaken on patients aged 18-49 attending one clinic over a six-month period. A feature of this survey was that each patient took part in a standard social interaction test, and their performance was assessed by two psychologists. A relatively high proportion of patients, one in six on the most conservative estimate, and probably over one in four, were judged by psychologists and psychiatrists to be socially inadequate, and the results showed a clear pattern of behavioural, social and personality factors associated with these judgements. Implications for assessment and treatment are discussed.

Adolescent