Search PubMed⌕ Search

Biomedical subjects

B Brambati

Publications and source records attributed to B Brambati.

At least 109 records · Page 6Linked to original sources

The intraventricular conduction time of fetal heart in pregnancies complicated by rhesus haemolytic disease.

The duration and shape of the fetal QRS complex were studied in 88 pregnancies complicated by rhesus isoimmunization. A clear correlation between ventricular depolarization time and haemoglobin levels at birth was observed. A single QRS value greater than 4 SD above the normal mean value, or a tendency to rapid increase was very suggestive of a bad prognosis, while a QRS duration below +4 SD or declining in sequential determinations reflects a temporary compensation of fetal conditions. From the QRS complex analysis a clear indication appeared of the constant and early involvement of the heart in terms of myocardial hypertrophy and/or cardiac enlargement. The sensitivity of QRS to anaemia and the feasibility of continuous non-invasive monitoring might allow, with the determination of bilirubin concentration in amniotic fluid, improvement in the management of rhesus haemolytic disease.

Blood Transfusion, Intrauterine↗

The intraventricular conduction time of fetal heart in uncomplicated pregnancies.

By means of a new averaging system, fetal electrocardiograms (ECGs) were obtained simultaneously from three orthogonal leads on the maternal abdomen. The duration of the QRS complex was measured in 421 pregnant women with uncomplicated pregnancies chosen at random between 17 and 41 weeks gestation. Normal standards were established and a close relation was found between QRS duration and the maturity of the fetus. A highly significant relation was observed in 78 patients between the birth weight and the QRS duration. Estimates of birth weight from QRS interval have a standard deviation of 302 g and this may allow the prediction of birth weight with reasonable accuracy. Information on the properties of the fetal ventricular conduction system can be derived from the data presented.

Birth Weight↗

International, collaborative experience of 1789 patients having multifetal pregnancy reduction: a plateauing of risks and outcomes.

OBJECTIVE: To develop the most up-to-date, complete data base of multifetal pregnancy reduction (MFPR) from cases, and to provide the best counseling for couples with multifetal pregnancies. METHODS: From nine centers in five countries, 1789 completed MFPR cases were collected and outcomes evaluated. Pregnancy losses were defined as through 24 weeks and deliveries categorized in groups of 25-28, 29-32, 33-36, and 37 or more weeks. RESULTS: Overall, the pregnancy loss rate was 11.7% but varied from a low of 7.6% for triplets to twins and increased with each additional starting number to 22.9% for sextuplets or higher. Early premature deliveries (25-28 weeks) were 4.5% and varied with starting number. Loss rates by finishing number were highest for triplets and lowest for twins, but gestational age at delivery was highest for singletons. CONCLUSIONS: Multifetal pregnancy reduction has been shown to be a safe and effective method to improve outcome in multifetal pregnancies. Outcomes are worse with higher-order gestations and support the need for continued vigilance of fertility therapy.

Abortion, Spontaneous↗