Search PubMed⌕ Search

Biomedical subjects

B Bonke

Publications and source records attributed to B Bonke.

At least 55 records · Page 3Linked to original sources

Shortening the State-Trait Anxiety Inventory.

Questionnaires that are used in studies with severely patients should be as short as possible. Abridged versions of existing inventories are very practical in these instances. The answers of 444 subjects in three samples (cancer patients, medical students, surgical patients) were used to investigate the possibility of constructing short and reliable versions of the scales of the State and Trait Anxiety Inventory. A stepwise regression procedure showed the possibility to reliably predict the total score of the unabridged versions by means of weighted sums of eight items for each scale. Omission of weights did not lead to substantial loss of information. Cronbach's alpha of the State-scale decreased from 0.93 to about 0.85 for different combinations of items and from 0.91 to about 0.82 for combinations of eight items of the Trait-scale. The relationship between both scales was only slightly modified by the shortening procedure.

Adolescent↗

Detection of lacunar infarction in brain CT-scans: no evidence of bias from accompanying patient information.

Interobserver agreement in assessing brain CT-scans is, in general, high. The extent, however, to which such agreement is caused by bias through knowledge of other clinical details remains uncertain. The hypothesis that observers are somehow prejudiced before assessing ambiguous CT-scans in this particular situation was tested. Sixteen neurologists and 16 radiologists volunteered to interpret two ambiguous brain CT-scans, with regard to the presence or absence of a lacunar infarct in the region of the internal capsule. The scans were accompanied by "patient" information that was or was not suggestive of a stroke. These scans were camouflaged by a variety of other scans, to be assessed in the same way, to mask the purpose of the study. It was assumed that the observers, in their assessments of the scans, would somehow let their ratings of the likelihood of a lacunar infarction in or near the internal capsule be subject to the accompanying information. Results showed lower ratings produced by neurologists (i.e., less likelihood of an infarction) than by radiologists in the majority of all assessments, but no bias by the accompanying information.

Cerebral Infarction↗

Auditory perception during general anesthesia: psychologic consequences.

Since the introduction of general anesthesia in the middle of the 19th century, incidents of auditory perception during general anesthesia have been reported in the medical literature. Most of these reports have dealt with purely medical issues, and surprisingly little has been written on the psychologic sequelae of these instances of auditory perception. We discuss the possible psychologic consequences of such perception, and suggest methods of treatment and prevention of the negative aspects of auditory perception during general anesthesia.

Aged↗

Effects of sounds presented during general anaesthesia on postoperative course.

In a double-blind, randomized study, patients undergoing cholecystectomy were administered one of four different sounds during general anaesthesia: positive suggestions, nonsense suggestions, seaside sounds or sounds from the operating theatre. The effect of these sounds on the postoperative course was examined to assess intraoperative auditory registration. No differences were found between the four groups in postoperative variables.

Adult↗

The stability of the A-Trait subscale of the STAI for stress and passage of time.

One hundred and eighty-eight surgical patients completed the A-Trait subscale of a Dutch version of the State-Trait Anxiety Inventory (STAI-DY) on the day before the operation and again 3 days later. A-Trait total-scores were significantly lower in the second measurement (p less than .01), and weighted kappa techniques showed disagreement in 8 of 20 pre-postsurgery items. Nine to 12 months postsurgery, 90 patients completed the measure again. Total-scores in session 3 were significantly higher than in session 2 (p less than .02), and 15 items showed disagreement between both sessions, with more agreement in Anxiety-present than in Anxiety-absent items. The ranges of the A-Trait score-changes between the different sessions turned out to be rather wide. These results indicate some instability of the A-Trait subscale of the STAI and argue for a cautious interpretation of individual scores.

Adolescent↗

Clinical study of so-called unconscious perception during general anaesthesia.

Ninety-one patients undergoing biliary tract surgery were randomly assigned to one of three treatment groups in which different sounds were administered, by means of earphones, in a double-blind design. The effects of the administration of positive suggestions, noise or operating theatre sounds on the postoperative course were studied. Results showed that exposure to positive suggestions during general anaesthesia, as compared with noise or operating theatre sounds, protected patients older than 55 yr against prolonged postoperative stay in hospital.

Adult↗

Stimulus processing during apparent unconsciousness in anesthetized volunteers.

Return of motor-responses upon request as an indicator of stimulus processing during apparent unconsciousness in general anesthesia was studied in 8 healthy, male volunteers during prolonged inhalation of nitrous oxide. First the minimal effective concentration of nitrous oxide was established for each volunteer, based upon continued absence of motor-responses to repeated verbal commands. One week later this concentration of nitrous oxide was administered for a 3-hr. period; return of motor-responses after at least 30 min. of absence was considered a sign of so-called unconscious perception. Four volunteers showed return of motor-response within the 3 hr. of exposure, but two of these had been rather restless throughout the session. Results indicate that unexpected processing of information by patients may occur during presumed unconsciousness after a prolonged inhalation of nitrous oxide in general anesthesia.

Adult↗

[Postanesthetic recall ability, anxiety and dreams in surgical patients. A clinical study].

The recall of stimuli registered during general anaesthesia is described. Patients were interviewed 2 days after surgery, concerning their experiences during anaesthesia. In a second series of observations, the interview was preceded by a short inquiry, which took place in the recovery room as soon as the patient awoke. Anxiety was also assessed by pre- and postoperative tests. Of 140 patients, 2 described recall of awareness during anaesthesia. There was no evidence that external stimuli had been incorporated into dream content.

Adolescent↗

Tolerance to nitrous oxide in volunteers.

Nociception and loss of awareness during exposure to anaesthetic concentration of nitrous oxide (N2O) were studied in eight male medical students. The cold water nociception test, where a hand is immersed in 0 degree C stirred water, was used for measurement of nociception. At irregular intervals an auditory command was given to oppose two fingers, and this served to monitor consciousness. The selected inspiratory concentration of N2O used per individual was sufficient to induce a loss of consciousness for more than 2.5 min, within 10 min of exposure to N2O. This concentration of N2O varied from 60% to 80%. The experimental exposure to N2O lasted 3 h. In all volunteers significant antinociception was observed within 2 min of exposure to N2O. The maximal analgesic effect was observed between 20 and 30 min of exposure to N2O. The analgesic effect of N2O gradually decreased and was absent in all eight volunteers within 150 min. Two volunteers regained consciousness at 77 and 91 min of exposure, whilst still breathing 60 and 80% N2O. These results show that tolerance to antinociceptive effects of N2O in man rapidly develops and that awareness may occur in some volunteers during prolonged exposure to N2O.

Adult↗