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Biomedical subjects

B Bloch

Publications and source records attributed to B Bloch.

At least 271 records · Page 15Linked to original sources
PubMed1977

[Immunocytological study of the gonadotrophic and thyrotrophic cells of the rat adenohypophysis].

On paraffin or semi-thin sections various anti-LH or anti-TSH sera stain indifferently all the thyrotrophs and the gonadotrophs. Inversely anti-beta-TSH, anti-beta-LH or anti-beta-FSH purified sera permit the discrimination of these two cell populations. The constancy of fixation of the anti-beta-LH and anti-beta-FSH sera on all the gonadotrophs gives evidence of their ability to produce both FSH and LH. However in a few female rats the central gonadotrophs are stained more weakly by anti-beta-FSH serum than by anti-beta-LH serum. The purification of the antisera by adjunction of hormonal antigens (alpha subunits or heterologous hormone) does not enable, with the PAP technique on thin sections, a selective staining of the secretory granules of the thyrotrophs or of the gonadotrophs.

Animals↗
PubMed1976

[Cytoimmunological demonstration of LH-RH neurons in the human fetus].

Neurons and axons were characterized by means of an antiserum against LH-RH in hypothalamus of human faetuses from the 13th week of gestation until birth. The morphology and the elective localization of neurons and axons in the mediobasal hypothalamus, premamillary area and in lamina terminalis, and the termination of axons, particularly those of the tubero-infundibular tract, are described. The results obtained permit discussion of hypothalamic control of gondotropic secretion in the human faetus from the 13th week.

Axons↗
PubMed1976

[Cyto-immunological study of the anterior pituitary somatotropin cells of male and female adult Peking, Barbary and hybrid (from crossing male Peking X female Barbary) ducks and of male ducklings of the 3 races)].

The anti-human-STH immunserum applied on hypophysis sections of adults males and females Peking (Anas platyrhynchos L.) Barbary (Cairina moschata L.) and Hybrid (from the mating male Peking X female Barbary) ducks, marks orangeophils, oval- or round shaped, PAS negative cells exclusively localized in the caudal lobe of the pars distalis. In the males ducklings of the three races this immunserum reveals numerous and partially exhausted cells. The authors conclude that the acidophils alpha cells observed in the caudal lobe of the duck are somatotrophic cells.

Age Factors↗
PubMed1976

[Comparative study in the guinea pig, cat and dog of hypothalamo-infundibular nervous fibers immunoreactive to an anti-LH-RH immune serum].

In the median eminence of guinea pig, cat and dog some axons of the hypothalamo-infundibular tract are immunoreactive with anti LH-RH. In these three species, the axons have a similar topography and area of peripheric terminations. These one occur at the capillaries of Mantelplexus. It was also shown, in the cat, that these areas of termination exhibit a strong monoamine fluorescence.

Animals↗
PubMed1976

[Immunocytochemical study using semi-thin sections of the phenomena of early differentiation in several cell populations of the human fetal adenohypophysis].

Immunocytological investigations have been performed on semi-thin sections of human fetal pituitaries ranging in fetal age from 6 to 26 weeks. Corticotrophs can be revealed by anti-ACTH (1-24), anti-ACTH (17-39) and anti-beta MSH but not by anti-alpha MSH immunesera from the 8th week. Somatotrophs are revealed with anti-human STH from 9th week. Differentiating cells containing only alpha subunits of glycoproteic hormones are present from 8th to 12th week. At 13th week beta subunits of TSH can be revealed immunocytologically in thyreotrophs. Beta subunits of LH or FSH can be detected in same gonadotrophic cells only from 15th week.

Adrenocorticotropic Hormone↗
PubMed1976

[Cyto-immunological studies of the gonadotropic cells of the human fetus].

The immunicytological analysis of PAE fixed semi-thin sections of pituitary cells (of human fetuses aged 6 to 26 weeks) using immunesera directed against the human total glycoproteic hormones, HCG, LH, FSH and TSH or made specific for the LH, FSH, and TSH beta subunits shows: -- the presence up to the 12th week of only the subunit of the glycoproteic hormones revealed indifférently by our anti total hormones immunesera; -- the apparition of the betaTSH subunits at the 13th week, characterizing the differentiation of the thyrotrophs; -- the apparition of betaLH and betaFSH subunits on the one and same gonadotropic cell population at the 15th week.

Animals↗
PubMed1976

[Immuno-cytologic study of LH-RH cells and fibers in the human fetus].

The application of immunofluorescence and immunoenzymology techniques with an anti LH RH I.S. permitted to reveal neurons and fibers in the human fetal hypothalamus from the 13th week up to birth. The morphology and dispersion areas of the neurons in the mediobassal, premammillary and anterior hypothalamus (lamina terminalis and its surroundings and the septum) as well as the direction and the destination of the immuno-reactive fibers of the hypothalamo infundibular tract have been described. These fibers are in contact with the capillaries of the Mantelplexus before and after the apparition of the intra-eminential loops at the 16th week. The general topography of the LH RH peptidergic system in the human fetus can be compared with the topography of other adult primates. The role of this system in the maturation and the control of gonadotropic cells is evoked.

Female↗
PubMed1975

Induction of labour with prostaglandin E2 tablets.

The induction of labour with prostaglandin E2 (PGE2) tablets in two dosage regimens, and with desamino-oxy-tocin, has been studied in association with amniotomy. In multiparas at or near term and with a high Bishop score. PGE2 appears superior with regard to the induction-to-delivery interval and the duration of labour, but both preparations are highly effective in this respect. In nulliparas with a low Bishop score, however, intravenous oxytocin after amniotomy is the method of choice.

Cervix Uteri↗
PubMed1975

Lynestrenol as a contraceptive preparation. Experience with a micro-dosage formulation.

Lynestrenol 0,5 mg was administered daily for a total of 1 082 cycles to 143 women of proven fertility and natural sexual activity. Twenty-three women withdrew from the trial for various reasons, the commonest of which were menstrual distrubances. No unplanned or accidental pregnancies occured. The menstrual disturbances tended to become less troublesome with continuation of treatment, and this was noted in relation to other side-effects, of which headache and loss of libido were initially the most troublesome.

Adult↗
PubMed1975

A study of the ultrastructure of the buffalo pox virus.

Buffalo pox virus (strain BP 4) has been studied by electron microscopy of sections of infected chorioallantoic membrane cells. The ultrastructure of the virus has been described and compared with the ultrastructure of vaccinia virus. No differences between the two viruses were found. In relation to the ways of release two forms of mature virions have been described. These are probably analogous to the previously described C- and M-form of vaccinia.

Animals↗
PubMed1975

The possible utilization of nuclear pockets of lymphocytes in the diagnosis of enzootic bovine leucosis.

A comparative study of the presence of lymphocytosis and nuclear pockets in lymphocytes was carried out using blood samples from animals belonging to herds with bovine enzootic leucosis and from herds free from leucosis. It was found that there was a correlation between the presence of such nuclear projections in a certain percentage of the lymphocytes and a state of lymphocytosis. As this correlation seemed to be independent of the aetiology of the lymphocytosis, it was not considered possible to employ the demonstration of nuclear pockets as a more specific tool in the diagnosis of bovine enzootic leucosis than the lymphocyte counts in themselves.

Animals↗
PubMed1975

[Immunocytochemical study of corticotropic cells in the adenohypophysis of the chick embryo].

Corticotrophin cells of the pituitary have been studied immunocytologically with I.S. anti-A.C.T.H. (1-24) and I.S. anti-A.C.T.H. (17-39). These sera show differentiated cells as soon as the 8th of incubation. These cells remain located within the anterior part of the adenohypophysis. They are not "revelated" by I.S. anti-beta-M.S.H. and I.S. anti-beta-LPH.

Adrenocorticotropic Hormone↗
PubMed1975

[Corticotrope and melanotrope cells in cat, fox, rat and human fetus adenohypophysis: studies with induced fluorescence, cytoimmunologic technics and lead hematoxyline].

Formaldehyde-induced fluorescence, acid-catalyzed or not, methods, and immunocytology with anti-ACTH (1-24), anti-ACTH(17-39), ANTI-BETA-LPH immunserums were applied on the same preparations of cat, fox, rat and human foetus pituitaries. The superpositions of results showed that the pars intermedia and pars distalis corticomelano-lipotrophic cells of fox and cat pituitary, those of human foetal pituitary, and the purely corticotrophics cells of the rat pars distalis contained a fluorogenic probably granular compound. Moreover, the granules of the same cell types were electively revealed on our lymphilized material by plombic hematoxylin. Only the anti-beta-LPH and/or anti-beta-MSH fixing celpls exhibited hypercyanophilic, PAS-positive and bleu alcian-positive caracteristics.

Adrenal Glands↗