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Biomedical subjects

B Becq-Giraudon

Publications and source records attributed to B Becq-Giraudon.

At least 127 records · Page 7Linked to original sources
PubMed1977

[Temporal arteritis and rhizomelic pseudo-polyarthritis. Clinical aspects and nosologic problems. Apropos of 48 cases].

The authors report 40 cases of temporal arteritis, of which 16 were associated with pseudo-polyarthritis, and 8 cases of polyarthritis alone. The clinical picture of temporal arteritis in the elderly, includes headaches in 95% of cases, clinical changes in the superficial head arteries in 75% of cases, joint and muscle signs dominated by pseudo-polyarthritis in 40% of cases; general signs were practically constant. A major inflammatory syndrome was also constant. From the histological point of view, there was pan-arteritis with giant cells, and their wide diffusion is shown by the presence of eye signs in 27.5% of cases, brain signs in 10% of cases, and extra-cephalic vascular signs in 10%. The relationship in classification between temporal arteritis and polyarthritis of the roots of the limbs is recalled. The course is long, the duration of corticosteroid therapy should never be less than two years; relapses are common but the mortality appears low.

Aged↗
PubMed1976

[Diabetes mellitus in pheochromocytoma].

The frequency of latent disorders of glucose regulation during pheochromocytoma, is evaluated at 75% of cases. Detailed analysis of 83 cases with a diabetic state, gave the following results: insulin dependent diabetes, 37 cases. Non-insulin dependent, 14 cases. Latent diabetes, 32 cases. The characteristics of the insulin-dependent diabetes were not always suggestive. Insulin dependency was, however, unusual above a certain age. We noted loss of weight in spite of good control of the diabetes, the absence of acidosis and ketosis contrasting with rapid loss of weight. In fact, it is above all the hypertension which should lead to diagnosis. Surgical operation, cures or improves considerably the diabetic state, thus proving the symptomatic nature of this diabetes.

Catecholamines↗
PubMed1975

[Botulism. Therapeutic management. Apropos of 36 cases].

Botulism is relatively common in the Vienne department as we have observed 36 cases over a peroid of 7 years. Other French cases, published over the last 10 years, included 10 to 19 cases in the largest series. In a total of 10 series, there were 105 cases. Botulism is caused, in most cases, by eating ham prepared on the farm. It gives rise to the usual clinical picture including paralysis of accommodation, dysphagia, digestive symptoms with abdominal pain and constipation and finally, bladder paralysis. The mild forms are fairly common. We did not observe any severe cases. Our patients were treated in two homogeneous series of 17 cases each ; two patients were given no treatment. Patients treated by sero-anatoxin therapy according to classical methods, evolved towards a cure within 21 days on average. Patients treated by sulfguanidin were cured within 24 days. This study permitted us to confirm that sero-anatoxin therapy is not essential. The disadvantages are the number of injections, the possibility of sometimes fatal hyper-sensitive reactions which, in the opinion of many authors, justifies routine cover with cortisone. This attitude does not seem to us justified owing to the usually benign nature of the botulism. The treatment with sulfaguanidin is well tolerated and is not of any risk to the patient.

Botulinum Antitoxin↗
PubMed1975

[Immunoglobulin D. Physiology and pathology excluding myeloma].

Immunoglobulin D is the fourth class of immunoglobulins secreted by the plasma cells and also, in 5% of lymphocytes, this is a surface immunoglobulin. Its serum levels are about 0.03 mg/ml, due to low secretion, intersititial diffusion and intense catabolism. IgD migrates on electrophoresis in the beta-gamma zone, on immuno-electrophoresis, in the beta2 zone. Only one disulphide bridge links the delta-chains together. The light chains, are, in most cases, lambda chain. Studies of the antigenic characteristics of the delta-chains are in progress. IgD does not take up complement, but has an antibody function. 37% of healthy subjects have anti IgD antibodies. Only 4 cases of monoclonal IgD gammopathy without malignant myeloma, have been reported. Anto-antibodies of IgD nature have been described in various connective tissue diseases or auto-immune processes.

Autoimmune Diseases↗
PubMedDate not supplied

[Mycoplasma pneumoniae infections. A multicenter retrospective study of 182 cases].

The spectrum of 182 hospital Mycoplasma pneumoniae infections, collected over a five-year period, is reviewed. The diagnosis was based on complement fixation test. Mycoplasma infection was encountered mainly in young people, mean age 29 years. Eighty-four per cent presented with an atypical pneumonia, 33 per cent had extrapulmonary manifestations mainly neurological and cutaneous. Acute respiratory failure occurred in 32 cases. Only 5 patients died. Macrolides or tetracyclines remain the most effective antibiotics but spontaneous recovery is usual.

Adolescent↗