Biomedical subjects
B Balme
Publications and source records attributed to B Balme.
[Linear infundibular hamartoma with basal cell carcinoma degeneration].
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[Pigmented nevus and cutaneous ossifications. Apropos of 125 cases of osteonevi].
In a series of 86,400 pathological examinations 125 cases of pigmented naevus associated with one or several foci of cutaneous ossification were observed. This association, known as osteonaevus of Nanta, account for 1.4 p. 100 of all pigmented naevi. In our series of examinations, osteonaevus was the most frequent cause (62 p. 100) of the 201 skin ossifications observed, the other causes being keratinizing basal cell epithelioma (7 p. 100) and pilomatricoma (5.5 p. 100). The patients' mean age was 46 years (range: 21-80 years), and 81 p. 100 of them were women. In almost every case the lesions were located on the head. The clinical diagnosis was always pigmented naevus, but it coexisted with inflammatory changes in 8 cases, and an underlying induration could be perceived at palpation in 4 cases. In 123 or ou 125 cases the pigmented naevus was restricted to the dermis, junctional theques being present in only 2 cases. The number of ossified foci varied from 1 in 45 p. 100 of the cases to 2 to 4 in 91 p. 100, and in 1 patient up to 8 foci were visible on the same section plane. The lesions presented as compact balls (135 cases), or lamellated bone (126 cases), or spicules of unorganized bone formations. They varied in size from 0.5 mm for balls to 1.5 mm for elements with a central cavity. In the latter were rudiments of bone marrow with capillary vessels, osteoclasts, adipose cells and cells that could be regarded as having haemopoietic functions. All naevi contained hair follicles.(ABSTRACT TRUNCATED AT 250 WORDS)
[Bullous photo-onycholysis during pseudo-porphyria due to hemodialysis].
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[Erosive adenomatosis of the nipple. Report of 10 cases with immunohistochemistry].
Erosive adenomatosis of the nipple (also called florid papillomatosis of the nipple ducts) is an uncommon disease since only 358 cases have been published. We observed 10 cases in 10 years, corresponding to 1 case in 8,500 skin biopsies. One of these cases concerned a male patient and is the 13th of this kind in the literature. In our series the mean duration of symptoms was 15 months, as against 25 months in the 121 published cases where duration was clearly specified. In 8 of our 10 cases the patients consulted for oozing erosion or discharge of the nipple. Physical examination showed a palpable nodule in 2 cases, a small pediculate tumour in 1 case and nipple enlargement in 50 p. 100 of the cases. The patients were followed up for as much as 7 years. The outcome was always favourable. Recurrence was observed in only one patient, 7 months after limited excision; 6 years after a second excision no relapse was noted. Histological examination showed a papillomatous lesion in 5 cases, an adenomatous lesion in 2 cases and a mixed lesion in 3 cases. Myoepithelial cells were found in all cases, but they were doubtful or discreet in 4 cases. The apical pole of columnar cells was labelled by the ACE antibody, but labelling was very weak and partial in 4 cases. The columnar cell cytoplasm was constantly and strongly labelled by the KL1 anti-keratin antibody. The apical pole of parietal cells was strongly labelled by the antiepithelial membrane antigen antibody (EMA) in all cases.(ABSTRACT TRUNCATED AT 250 WORDS)
[Diagnostic trends in the microscopic discovery of mucinous deposits].
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[Acquired genital leukokeratosis in epidermolytic hyperkeratosis].
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[Kaposi's sarcoma].
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[Pachydermatodactyly associated with plantar pachydermy].
INTRODUCTION: Pachydermodactyly is a superficial fibromatosis located on the proximal portion of fingers'phalanges and interphalangeal joints. Several types of this disease have been described depending on topography, etiology and pathological associations. We report a typical observation of pachydermodactyly associated with a plantar pachydermy. CASE-REPORT: A 19 year-old man was followed for a psychotic disease, associated with mental retardation. On clinical examination, he showed a typical pachydermodactyly, predominantly located on the second, third and fourth fingers of both hands, associated with recent acrocyanosis. A pachydermic aspect was also observed on the external part of the feet sole. Histopathological analysis was identical on digital and plantar lesions with collagen swelling. These lesions extended into the subcutaneous fat only in the feet. DISCUSSION: This observation is compatible with the most classical form of pachydermodactyly which involves several fingers of both hands, usually in men. Furthermore, the association with a psychiatric disorder and the notion of repeated traumatisms have been frequently reported in the literature. However, acrocyanosis and the important disability observed in our case are unusual. Association with plantar pachydermy has never been reported. The identical histological aspect on finger and feet sole suggests that pachydermatodactyly should be integrated in framework of acral pachydermy.