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Biomedical subjects

B Büky

Publications and source records attributed to B Büky.

At least 19 recordsLinked to original sources
PubMed1990

[Wolf-Parkinson-White syndrome in neonatal age].

Description of history data, course of the disease and therapy is given of WPW syndrome diagnosed in neonatal age. In connection with the case the authors deal in details with the etiology, pathomechanism, course and complications of the disease. Problems of differential diagnostics and therapy are discussed. A relatively infrequent case is presented; the importance of pre- and postnatal observation and diagnosis being in close connection with the way of therapy and prognosis is emphasized.

Amniocentesis↗
PubMed1990

Treatment of severe hyaline membrane disease with surfactant (Curosurf). A collaborative clinical study.

We investigated the clinical efficacy of a new surfactant product, Curosurf, isolated from porcine lungs by liquid-gel chromatography. Ten premature newborn infants (birth weight 850-1850 g), all ventilated artificially for severe hyaline membrane disease categorized radiologically as stage III-IV, received a single dose of Curosurf (200 mg/kg) via the tracheal tube. This treatment resulted in a rapid improvement of oxygenation, similar to that observed by other teams collaborating in the study and, in an astonishingly fast resolution of the radiological changes. In comparison with a control group of 8 infants, the surfactant-treated babies also had a lower incidence of acute and chronic complications.

Biological Products↗
PubMed1987

Respiratory distress syndrome: steroid and peptide hormone levels in maternal venous blood and the umbilical vein and artery.

The concentration of steroid and peptide hormones in the development of the respiratory distress syndrome of the newborn has been investigated. Serum progesterone, dehydroandrostenedione sulphate (DHAS) oestradiol, oestriol, cortisol, prolactin and human placental lactogen (HPL) concentrations were measured by radioimmune assay (RIA) in samples obtained from the maternal vein and the premature newborn's umbilical artery and vein. The results were grouped according to gestational age into two groups, 28-32 and 33-36 weeks. Serum cortisol level was lower in maternal blood and both the umbilical vein and artery if the newborn subsequently developed RDS. No deviations from healthy values were encountered with any other hormone. These observations and data in the literature suggest that maturation of the fetal lung is influenced not only by maternal glucocorticoid secretion but also by the activity of the fetal adrenal cortex.

Female↗
PubMed1985

[Not Available].

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Czechoslovakia↗
PubMed1982

The role of degradation of fetal haemoglobin in the energy supply of very low body weight pre-term babies.

Low body weight premature babies born before the 32nd gestational week were studied to analyse the postnatal fall in plasma haemoglobin and in quantitative changes in amino acid levels. Red blood cells of premature low body weight infants were found to disintegrate more rapidly than those of mature newborns. Thin-layer ion-exchange chromatographic studies showed that amino acids originating from the degrading haemoglobin-F lead to rise in plasma amino acids. These amino acids might play a role as substrates for gluconeogenesis in the energy supply of low body weight premature babies during the special fasting state just after birth.

Amino Acids↗
PubMed1979

Alterations in creatinine clearance during respiratory distress syndrome.

Some renal parameters have been studied in newborns with respiratory distress syndrome (RDS). During the first 24 h, the serum creatinine level of the severe cases of RDS are significantly increased, decreasing gradually with improvement of the RDS and reaching normal values within 10 days. Blood urea nitrogen remained unchanged. In the milder cases of RDS, the serum creatinine also showed a slighter increase, which became normal within 4 days after birth. During the acute phase of RDS, there is a reversible impairment in the renal function, which correlates with the degree of hypoxia, hypercapnia and acidosis determined by the primary disease.

Blood Urea Nitrogen↗
PubMed1979

[Not Available].

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History, Ancient↗
PubMed1978

[Fine structure studies in the lungs of infants with idiopathic respiratory distress syndrome].

Authors studied ultrathin cestions of lung of ten newborns died of IRDS in the various stage of the disease. It was established that lamellar bodies are already formed in the initial phase of the disease. In the first two clinical phases by pneumocytes type II structure of the intracytoplasmic and intaraalveolar lamellar bodies differs from the normal, and they can not form air-cell interphase. In the third clinical phase--in the phase of the resolution-mature lamellar bodies of normal structure are formed and get into the alveolar space, thus the condition of formation of air-cell interphase is given.

Autopsy↗
PubMed1976

[Arvin anticoagulant for prolonged extracorporeal membrane oxygenation (author's transl)].

Treatment of overwhelming but reversible respiratory failure has broadened to include extracorporeal support with a membrane lung. Until recently, it has been necessary to rely on heparin to prevent clotting in an extracorporeal circuit. During prolonged bypass heparinisation may be attended by bleeding. We investigated the use of arvin for systemic anticoagulation in extracorporeal membrane lung bypass in lambs. Arvin is a purified fraction of the venom of the Malayan pit viper. Effective anticoagulation was obtained for an average of 4 days (range 2 to 12 days) through complete fibrinogen depletion by arvin. These preliminary data suggest that arvin anticoagulation may be suitable for prolonged extracorporeal membrane oxygenation.

Animals↗
PubMed1976

Idiopathic respiratory distress syndrome: acoustic, laryngoscopic and radiological investigation.

The breathing pattern in IRDS has been analysed by sound recording, direct laryngoscopy and chest X-rays. The reflex mechanism operative in IRDS was found to be a modified version of the Hering-Breuer reflex; in a certain phase of inspiration the respiratory muscles relax and passive expiration begins. In IRDS, at the end of the short inspiratory phase accompanied by grunting the glottis is suddenly closed, and collapse of the alveolar space is prevented. The small opening of the glottis before the next inspiration serves the same purpose, and the air passing through it is heard as grunting. As soon as the alveolar space is emptied, the glottis becomes wide open and a quick inspiration follows. The modified Hering-Breure reflex increases the respiratory tract pressure and thus prevents collapse of the alveolar space. When the newborn is no longer capable of the excess extra work required for grunting, the decompensated phase of IRDS sets in. Gas exchange rapidly deteriorates and the white lung pattern is visible on the chest X-ray.

Glottis↗