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Biomedical subjects

B B Wray

Publications and source records attributed to B B Wray.

53 records · Page 3Linked to original sources
PubMed1981

Recurrent purulent triaditis in a patient with congenital x-linked agammaglobulinemia.

A patient with congenital x-linked agammaglobulinemia, who had two separate episodes of an apparent bacterial purulent hepatic triaditis in the absence of any known local predisposing factors, is presented. These episodes may reflect the increased susceptibility of an immunodeficient patient to bacterial infections. This case demonstrates the need to consider hepatic involvement in the work-up of fevers of undetermined origin in immunodeficient patients, even in the absence of any radiologic or sonographic evidence of mechanical biliary tract obstruction.

Agammaglobulinemia↗
PubMed1980

Nephropathy in the Wiskott-Aldrich syndrome.

Nephropathy was detected in five of 32 patients with the Wiskott-Aldrich syndrome who were participating in a study of transfer factor (TF) therapy. In two patients, nephropathy was present before TF and did not appear changed by TF therapy. One of these patients subsequently developed progressive renal failure requiring dialysis beginning 5 1/2 years after TF therapy. In two patients, decreased renal function appeared very soon after the administration of TF. One patient showed gradually decreasing renal function beginning after two years of TF therapy. An additional patient was identified who died with renal failure without having received TF. The results suggest that renal failure occurs in the Wiskott-Aldrich syndrome more frequently than generally recognized and that administration of TF may precipitate or accelerate the renal disease in patients with this syndrome.

Adolescent↗
PubMed1978

Pharmacologic management of asthma in childhood.

New drugs such as inhalable corticosteroids, disodium chromoglycate, and selective beta2 sympathomimetic agents, as well as new understanding of pathophysiologic mechanisms of older drugs, enable better pharmacologic management of the child with asthma. Emphasis is on educating patient and parents and on using doses calculated for weight of anhydrous theophylline equivalent as well as for beta agonists. Preventive environmental measures should always be used in conjunction with drug therapy.

Adrenal Cortex Hormones↗
PubMed1975

Mycotoxin-producing fungi from house associated with leukemia.

Fungi were isolated from a house associated with four leukemic patients from three families because of the possibility that mycotoxin-producing strains might be present. Extracts of several of the isolated fungal species produced toxic effects in one or more species of animals. Aflatoxin-producing Aspergillus parasiticus was isolated from non-leukemia-associated houses with the exception of Trichoderma, Verticillium, and Monotospora. We believe that certain mycotoxins may be related to pathogenesis of leukemia, possibly as an expression of their immunosuppressive effects.

Adult↗
PubMed1971

Airborne allergens.

Explore the source record for details and available documents.

Air Microbiology↗
PubMedDate not supplied

Suppression of phytohemagglutinin response by fungi from a "leukemia" house.

Fungal isolates from the house of a husband and wife who both developed acute myelomonocytic leukemia were assayed for effects on the in vivo response to phytohemagglutinin in guinea pigs. Skin responses to intradermal phytohemagglutinin were measured following injections of sterile fungal extracts. Isolates of Penicillium canescens, Curvularia, Fusarium sambucinum, Fusarium equiseti and Trichoderma koningii from the leukemia-associated house depressed the responses to phytohemagglutinin, but none of the fungal isolates obtained from a nearby control house depressed responses to phytohemagglutinin. Such environmental agents may contribute to development of malignancy by suppression of immune responses.

Aged↗