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Biomedical subjects

B B Gupta

Publications and source records attributed to B B Gupta.

At least 55 records · Page 3Linked to original sources
PubMed1982

A three-layer semi-empirical model for flow of blood and other particulate suspensions through narrow tubes.

A three-layer mathematical model has been developed and tested for calculating the velocity profile and wall layer thickness for the flow of blood and other particulate suspensions in narrow tubes, from measurements of apparent viscosity and mean concentration in tube. The model consists of a thin cell-free layer, accounting for wall exclusion effect, a cell-depleted one due to radial cell migration and a central core with uniform cell concentration. It is shown that this model contains several previously published models as particular cases and that it gives more realistic predictions of velocity profiles from the same data than less refined models. With proper adjustment of its parameters it is applicable satisfactorily to a wide variety of suspensions. The model results confirm the importance of cell deformability on blood rheological properties in capillaries less than 100 mu.

Blood Circulation↗
PubMed1981

A one-dimensional model of simultaneous hemodialysis and ultrafiltration with highly permeable membranes.

A one-dimensional model of combined convective and diffusive mass transfer in a hemodialyser is presented. Solutions and results are given for two regimes of ultrafiltration (UF): at low transmembrane pressures when UF flow is proportional to transmembrane pressure and in the limit of large transmembrane pressures when UF is limited by protein concentration polarization. It is found that the overall clearance is always less than the sum of dialytic and UF clearances due to interaction between convective and diffusive transfers. For a given UF flow the clearance is not sensitive to UF flux distribution along the membrane. Model predictions of urea clearance are in good agreement with measurements obtained in vitro with saline on hemodialysers equipped with a polyacrylonitrile membrane.

Blood↗
PubMed1972

Chronic Budd-Chiari syndrome due to obstruction of the intrahepatic portion of the inferior vena cava.

Clinical features of obstruction of the intrahepatic portion of the inferior vena cava were observed in five out of the 11 patients with the Budd-Chiari syndrome seen during the last four years. These patients apparently formed a distinct group from the remaining six and resembled in clinical course, biochemical features, haemodynamic findings, and radiological investigations the patients described as cases of membranous obliteration of the intrahepatic portion of the inferior vena cava. The present study reports five such patients diagnosed with the help of venous catheterization, percutaneous hepatography, and haemodynamic studies. The value of distinguishing these patients from those with obstruction due to hepatic vein occlusion is highlighted because of the difference in the prognosis and treatment.

Adolescent↗