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Biomedical subjects

B B Brody

Publications and source records attributed to B B Brody.

7 recordsLinked to original sources
PubMed1985

Isolation of Klebsiella ozaenae from a corneal abscess.

In this report, a case of bacterial keratitis caused by Klebsiella ozaenae is presented. The patient was an otherwise healthy 65-year-old woman with a history of chronic ocular inflammation and a corneal transplant two years prior to the appearance of the corneal ulcer. K. ozaenae is uncommon as a cause of keratitis and is recognized as a cause of atrophic rhinitis and as an opportunistic pathogen in patients with various underlying diseases. The organism was not identified with the computer-assisted API 20E for identification of the Enterobacteriaceae, and conventional methods were required to demonstrate its unique properties. The clinical spectrum of disease, the characteristics of the organism, and its susceptibility to antimicrobial agents are discussed.

Aged↗
PubMed1983

Multilayer film analysis: evaluation of ion-selective electrolyte slides.

We evaluated the Kodak Ektachem multilayer ion-selective electrolyte slides. For various types and concentrations of control material the precision (CV) within- and between-day ranged from 0.5 to 1.3% (1.7-2.1%) for sodium, 1.2 to 2.2% (2.7-2.9%) for potassium, 2.9 to 4.6% (5.9-6.7%) for carbon dioxide, and 0.7 to 1.6% (1.3-1.4%) for chloride. For all these analytes, analytical recovery was about 100%, except in the supra-physiological ranges, for which carbon dioxide recovery was about 110-120%. Either serum or heparin-treated plasma can be used, interchangeably, for analysis; use of serum treated with lithium iodoacetate is unacceptable. Comparisons with results by continuous-flow procedures demonstrated good correlation for sodium, potassium, and chloride; carbon dioxide comparisons indicate an Ektachem calibrator change may be required. Abnormally low protein concentrations or lipemia had no observed effects on results for electrolytes. Abnormally high protein concentrations affect sodium results slightly (approximately 5 mmol/L).

Autoanalysis↗
PubMed1978

The significance of the MB isoenzyme in patients with acute cardiovascular disease with a normal or borderline total CPK activity.

CPK MB isoenzymes were qualitatively identified using an electrophoresis method in 166 patients with acute cardiovascular disease during a six month period. Forty-three had total CPK activity in the normal or borderline range (0--75 U/Liter at the time the MB isoenzyme was first identified. Fifteen of these patients were diagnosed as having had a new acute myocardinal infarction (Group I) and another 15 as having had an old myocardial infarction (Group II). Diagnosis was based on electrocardiographic changes or autopsy findings. The remaining 13 patients were classified as "ischemic heart disease" (Group III) in the absence of strict electrocardiographic criteria or autopsy evidence of myocardial infarction. Nine of the 15 patients in Group I subsequently had elevations of their total CPK activity above 75 U/L. In contrast the total CPK activity of only one patient from Group II and Group III subsequently exceeded 75 U/liter. All 43 patients had evidence of cardiovascular disease. Our findings suggest that the detection of MB isoenzyme in the presence of a normal total CPK activity is a significant laboratory finding and is indicative of cardiac myofiber injury.

Acute Disease↗
PubMed1978

Radioimmunoassay of serum myoglobin: evaluation and modification of a commercial kit and assessment of its usefulness for detecting acute myocardial infarction.

We evaluated a modified procedure for a commercially available myoglobin radioimmunoassay kit (Nuclear Medical Systems). Within-run and run-to-run precision was acceptable. Normal ranges were established and paralelism studies performed. Clinical usefulness was assessed in 100 consecutive patients admitted to our coronary-care facility. The determinations were done daily, along with creatine kinase and its isoenzymes, and lactate dehydrogenase and its isoenzymes. Fifty of the 100 patients ultimately were shown to have had acute myocardial infarction. Myoglobinemia was present in most of the patients with acute myocardial infarction, but information on its presence was less usefull clinically than was detection of creatine kinase isoenzyme MB.

Creatine Kinase↗
PubMed1971

Why fraternities?

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Dentistry↗