Search PubMed⌕ Search

Biomedical subjects

B Andersen

Publications and source records attributed to B Andersen.

At least 199 records · Page 11Linked to original sources
PubMed1977

Abdominal scintiphotography with 99mtechnetium-labelled albumin in acute gastrointestinal bleeding. An experimental study and a case-report.

In a new diagnostic method in acute gastrointestinal bleeding, after an intravenous injection of 99mtechnetium-labelled albumin, the distribution of radioactivity in the abdomen is followed for 40-60 minutes by sequential scintiphotography. The site of simulated gastrointestinal bleeding could be identified in all five volunteers. In a patient with severe bleeding from diverticula in the sigmoid colon the method gave a correct estimate of the site of the bleeding and of its rate.

Abdomen↗
PubMed1976

A double-blind trial of baclofen against placebo in the treatment of schizophrenia.

Twenty male chronic schizophrenic patients participated in a double-blond between-patient study of the GABA-like drug baclofen to evaluate the antipsychotic effect of baclofen. No difference was found between the 10 patients who received baclofen and 10 who received placebo with regard to the number of days before a worsening of their psychiatric condition necessitated treatment with chlorpromazine, the total score for psychotic symptoms before and after treatment for 10 weeks, or the total consumption of chlorpromazine. Discontinuation of baclofen did not exacerbate the psychotic symptoms. Baclofen was superior to placebo in the treatment of anxiety, which is of particular interest in view of the recent theories on the mechanism of action of benzodiazepines. The relationship between the gabergic system and the dopaminergic system with regard to the substantia nigra and the corpus striatum is discussed as well as the suggestion based on animal experiments that baclofen has an antipsychotic effect.

Adult↗
PubMed1976

Value of routine estimation of erythrocyte sedimentation rate in surgical patients.

The value of the erythrocyte sedimentation rate (ESR) as a screening test has been assessed through a retrospective analysis of 1648 surgical patients, in whom this test was not necessary for diagnosis, treatment or evaluation of risk factors. The ESR was inexplicably elevated in 42 patients (2.5%), but a marked increase was found in only very few cases, and in none had this finding been of any consequence for the admission in question. One patient had a malignant disease, which was not diagnosed during hospitalization, but the reasons for this were incorrect interpretation of relevant diagnostic procedures. We conclude that ESR can be excluded as a screening test in surgical patients, when diagnosis and therapeutic measures can be decided by history-taking and physical examination.

Blood Sedimentation↗
PubMed1975

An unusual outbreak of brucellosis.

A Brucella melitensis infection involved three persons. The infections were acquired by contact with a culture suspension that had been spilled during a laboratory exercise. One of the patients had only indirect contact with the spilled culture, probably contact with contaminated fomites. Another of the patients developed a clinical remission before treatment with antibiotics and relapsed after six months. This patient also had a positive bone marrow culture when blood cultures were negative. The type of antibody response persisting in the sera of convalescents was studied by treating the sera with mercaptoethanol and rabbit antihuman IgM sera. In the patient who relapsed, IgG antibody predominated, whereas IgM persisted for over two years in the patient without relapsing disease.

Adult↗
PubMed1975

Survival of patients with untreated liver metastases from colorectal cancer.

In 105 patients with colorectal cancer, liver metastases were found at extirpation of the primary tumor. The spontaneous survival was a median of 10 months. The intraoperative clinical diagnosis of liver metastases was subsequently confirmed by autopsy in 77 patients, was uncertain in 26, and was proved wrong in two at subsequent celiotomy. The accumulative experience shows that the median survivals range from 6 to 12 months, which is considerably better than in unselected series of liver metastases.

Colonic Neoplasms↗
PubMed1975

Distribution of disaccharidases, alkaline phosphatase, and some intracellular enzymes along the human small intestine.

The longitudinal distribution of various enzymes along the human small intestine was studied by analysis of biopsies from different parts of the small intestine, obtained from 13 patients during shunt-operation for severe obesity. Alkaline phosphatase and 3 glycolytic enzyme activities studied were rather uniformly distributed along the small intestine. Acid beta-galactosidase and hetero beta-galactosidase activities were highest in the proximal small intestine with a gradual decline throughout the intestine. The activity in the distal ileum was about half of the maximum activity. Maltase, isomaltase, sucrase, and trehalase activity had a broad maximum in the proximal and middle small intestine with a rather sharp decrease in the distal ileum. Lactase activity had a more pronounced maximum in the middle intestine with a pronounced decrease towards the proximal and distal ends. The disaccharidase activities in surgical biopsies taken 5 cm distal to the ligament of Treitz were about 10% higher than in peroral biopsies taken just at the ligament.

Adult↗