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Biomedical subjects

B Aeikens

Publications and source records attributed to B Aeikens.

32 records · Page 2Linked to original sources
PubMed1980

[Studies of the morphological and morphometrical changes in the rat nephron after unilateral ureteral ligation (author's transl)].

The influence of unilateral ureteral ligation in the rat nephron has been morphometrically analysed. The glomeruli show no significant differences compared with the control groups. The lumen of the tubulus rectus I increases significantly, but irregularly, after the 6th day of ureter ligation. The brush border is mostly destroyed after the 8th day. The tubulus rectus II changes only very little during this period. At the beginning of the ligation the lumen dilates, and at the end of the experiment the tubulus becomes normalised. The most important changes have been seen on the collecting tubules. As a consequence of increased intratubular pressure the lumina continuously dilate.

Animals↗
PubMed1980

[The influence of completely ligated ureters on the regeneration of tubulus cells after diversion of the urine by ureterocystoneostomy (author's transl)].

After a complete destruction of the ureter, renal function recovers more completely after diversion of the urine by splints than by ureterocystoneostomy. After a longer period of obstruction and successive restoration of urinary diversion by ureterocystoneostomy a relative increase in pressure of the ureter continues. This is the result of a functional obstruction, caused by disintegration of the muscle cells by connective tissue. The proliferation of connective tissue is probably induced and maintained by extravasation of urine into the layers of the ureter and that after abolition of the special function of the tunica mucosa. The defects of the mucosa are probably caused by metabolic disturbance after a pressure-induced decrease of blood supply.

Animals↗
PubMed1980

[Caryometry for testing the effectiveness of hormone treatment of carcinoma of the prostate gland (author's transl)].

Control aspiration biopsy should be performed on patients with carcinoma of the prostate gland, because the tumour cells show morphological signs of regression if estrogen therapy is successful: the nuclei of the tumor cells shrink. This can be measured by caryometry. In tumors refractory to estrogen primarily, the nuclei fail to shrink, whereas in tumors refractory to estrogen secondarily, the nuclei reexpand. The cytologic-caryometric findings are therefore an important means of assessing the effectiveness of hormone therapy.

Biopsy↗
PubMed1980

[The segmentation of urinary cells--a first step in the automated processing in urine cytology (author's transl)].

By segmentation of cell images we understand the automated decomposition of microscopic cell scenes into nucleus, plasma and background. A segmentation is achieved by using information from the microscope image and prior knowledge about the content of the scene. Different algorithms have been investigated and applied to samples of urothelial cells. A particular algorithm based on a histogram approach which can be easily implemented in hardware is discussed in more detail.

Autoanalysis↗
PubMed1980

[A cytophotometric study of urothelcells with a combination of MPV and A.S.M. (auther's transl)].

The frequency of bladder carcinoma is increasing all over the world. In civilized countries the cause of the increasing frequency is depending on environmental factors of different kinds. The cytologic examination of the urine has proved itself as a screening test for papillomas and carcinomas. With the help of the urine cytology it is possible to detect the cancer of teh bladder frequently at a time, when an operative treatment is still successfull. Tumors of low malignancy (grade I) reveal minor abnormalities and therefore these tumors are often overlooked using cytological methods. For these reasons it is desirable to develop methods for further characterisations of the tumors. Therefore, it appeared useful to examine the applicability of microscopic scanning cytophotometry to discriminate urothelial cells. A special combination of MPV and A.S.M has been built for reasons of interactive segmentation of the cell into nucleus, plasma and background. Computer discrimination between benign, atypical and malignant cells by means of cytophotometry has been accomplished with a small error of classification, not greater than five percent.

Cell Nucleus↗
PubMed1977

[The construction of models intending spatial representation of complex vessel structures demonstrated by means of the mammalian glomerulus].

This report presents information about a method to construct a wax-sheet model of rat and human glomerula, able to be divided into several segments. Based on the wax model consisting of segments a glomerula model is developed, showing the axis of the glomerula capillaries formed by an ironwire. By means of this model it will be possible to follow the course of the capillaries precisely.

Animals↗
PubMed1976

[The clinical significance of extratesticular originating tumors (author's transl)].

A case of large retroperitoneal metastasis of a seminoma is demonstrated. The primary tumor was impossible to recognize clinically. The extremely scarred primary tumor was at last discovered histologically in the normal appearing testis on the same side. This experience leads to the conclusion that the diagnosis "extratesticular originating testicular tumor" not be accepted unless a "burned-out" tumor can be exluded histologically in the ipsilateral testis.

Adult↗
PubMed1975

[The structure and function of the vena spermatica interna--the etiology of varicocele].

From 60 male corpse in the age of 13 to 77 both venae spermaticae internae were completely removed. On the basis of these specimens we investigated the incidence, localization, form and scale of the venous valves in the vena spermatica interna. All venous valves were remodeled and examined for their sufficiency on the basis of these date. In the left vena spermatica interna we found in 83% and in the right vena spermatica in 97% of the cases one or more valves. On the average the left vena spermatica contains 3.5 and the right 3.8 valves. From each vein a drawing was made, showing the remification, the localization of the valves and the valvular function. On the basis of this drawing and reconstructions of valves in the left vena spermatica interna for 90% of the cases and in the right vena spermatica for 75% of the cases a retrograde flow of the blood is possible. The absence of a varicocele can be explained by the presence of a sufficient venous valve on the left side in only 10% and on the right side in 25% of our cases. For the development of a varicocele therefore further facts are of importance.

Adolescent↗