Search PubMed⌕ Search

Biomedical subjects

B A Volel'

Publications and source records attributed to B A Volel'.

4 recordsLinked to original sources

[Involutional hysteria as a form in dynamics of personality disorder].

Forty patients (37 women, 3 men, age 47.3 +/- 3.4 years) with diagnosis of involutional hysteria (IH) have been studied. Two variants of IH have been identified. The first one, hystero-hypochondriac, is characterized by a prevalence of conversions, asthenia and hypochondria; the second--by hysterical depression, overvalued erotomania with premorbid histrionic personality disorder. The hypochondriac variant of IH is triggered by somatogenic disorders (gynecological surgeries, cardiovascular diseases) as well as various psychogenic factors (conflicts in professional and family life). Manifestation of the second variant is realized by the mechanism of key feeling, with trigger factors related to the objects of overvalued events (adultery, break-up of love affairs).

Adult↗

[The experience of pyrazidol use in the treatment of non-psychotic depression].

Pirazidolum ("Masterlek", Russia) was used in the treatment of 30 patients with recurrent depression (ICD-10 item F33) and depression episode (F32), mild and moderate types. The initial dose was 50-75 mg daily, mean dose--200-350 mg daily, treatment course--28 days. The efficacy of the treatment was evaluated by Clinical Global Impression (CGI) scale, Hamilton depression (HAM-D) scale and side effects scale (UKU). Significant improvement was revealed in 73% of the patients. A trend to improvement scored on HAM-D was detected by 2 treatment week 2, and pronounced improvement (more than a half-decreased total score)--by week 4. Only 27.6% of the patients had weak side effects (dry mouth, sweatiness, tachycardia etc) that did not demand any changes in the treatment course. The authors believe that pirazidolum may be referred to antidepressants which are effective for depression with a prevalent positive affect.

Adolescent↗

[Clinical aspects of "folie du doute"].

"Folie du doute" related to obsessive disorders manifests with doubts about managing habitual actions, reality of what is happening and existence of surrounding subjects; ruminations, indecision emerged as incapability to choose a definite behavior line. Sixty-six patients, 27 men and 39 women (mean age 31.3 years) have been examined. Three clinical "folie du doute" variants were distinguished: "repeated control" obsessions (doubts are realized by re-control of the actions committed); obsessive doubts defined by contrastive ideas of expedience for choosing the approach contrastive to the taken decision; anxious ruminations (lack of assurance in the past actions and obsessive doubts of the variants supposed-to-be). "Folie du doute" emerged in different psychic disorders, the first variant manifesting in the scope of neurotic-like schizophrenia; the second one--in psychogenic states or psychogenically-provoked exacerbations of psychopathic-like schizophrenia; the third one being regarded in the structure of cyclothymiac's depressive phases. In the clinical contest, "folie du doute" manifestation proves to be unfavorable prognostic marker.

Adult↗

[Obsessive doubts by contrast].

Obsessive doubts by contrast, along with traditional obsessions, refer to a kind of obsessive states, for which contrast content presentations provide a basis for obsession appearance accompanied by irresistible drive for walking off a psychogenic situation. Obsessive doubts by contrast are formed due to a conflict between equally attractive but incompatible wishes. The content of contrast throught is not absurd but reflects a real traumatizing situation. A study of 28 patients revealed they have psychasthenic accentuation as a personal feature in common. Obsessive doubts by contrast may develop both in the terms of affective disorders and schizotypical disorder (slow progredient schizophrenia). They have current character and in a number of cases transform into other obsessive-phobic states.

Adult↗