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Biomedical subjects

Ayse Yagci

Publications and source records attributed to Ayse Yagci.

6 recordsLinked to original sources

Quality of vision following clinically successful penetrating keratoplasty.

PURPOSE: To evaluate visual function following clinically successful penetrating keratoplasty (PKP). SETTING: Department of Ophthalmology, Ege University, School of Medicine, Izmir, Turkey. METHODS: Patient group (PG) included 9 patients (12 eyes) who had clinically successful PKP in our department. The control group (CG) included 12 people (18 eyes) who had no ocular disease other than refractive errors. Those with a visual acuity level less than 20/25 were not included in the study. Contrast sensitivity levels and light threshold values of the central retina were measured; scanning-slit corneal topography-pachymetry and aberrometric analysis were performed. RESULTS: There were no statistical difference in terms of age (32.55 years +/- 9.25 (SD) in PG, 36.75 +/- 5.85 years in CG; P =.53), cylinder power in plus form (2.60 +/- 1.25 diopter (D) in PG, 2.79 D +/- 2.51 D in CG; P =.88), and spherical equivalent of refractive errors (-3.66 +/- 3.57 D in PG, -5.52 +/- 3.37 D in CG; P =.29) between the PG and CG. Cambridge low-contrast grating scores were 96.5 +/- 41.1 in grafted eyes and 148 +/- 27.7 in CG (P =.004). Central retinal light sensitivity was measured as 29.91 +/- 2.39 db in PG and 33.08 +/- 1.56 db in CG (P =.001). In corneal topographic analysis, mean kappa intercept was 0.69 +/- 0.37 mm in PG and 0.55 +/- 0.24 mm in CG (P =.20). Lower-order Zernike root mean squares (RMS) were 7.30 +/- 3.89 microm for PG and 8.58 +/- 3.46 microm for CG (P =.37). However, higher-order Zernike RMS were 2.15 +/- 0.78 in PG and 0.38 +/- 0.10 in CG, which is a statistically significant difference (P<.001). CONCLUSIONS: Even though the clinically successful PKP patients have correctable amount of spherocylindrical refractive errors with spectacle lenses, they still have reduced visual quality because of the significantly high amount of higher- order aberrations when compared with naturally occurring refractive errors.

Adult↗

Surgically induced corneal refractive change following glaucoma surgery: nonpenetrating trabecular surgeries versus trabeculectomy.

PURPOSE: To compare surgically induced corneal refractive change following trabeculectomy with the nonpenetrating trabecular filtering surgeries with and without implant. SETTING: Department of Ophthalmology, Ege University School of Medicine, Izmir, Turkey. METHODS: A consecutive series of 34 patients (34 eyes) with uncontrolled open-angle glaucoma had trabecular filtering surgery. Patients were assigned randomly to receive viscocanalostomy (12 patients), nonpenetrating deep sclerectomy (NPDS) with T-flux implant (10 patients), and trabeculectomy (12 patients). Autokeratometry and computerized corneal videokeratoscopy with the Topcon KR-7000P autokeratorefractometer were performed preoperatively and 1 day and 1, 3, and 6 months postoperatively to analyze surgically induced keratometric and topographic astigmatism. RESULTS: Thirty patients (11 trabeculectomy, 11 viscocanalostomy, and 8 NPDS with nonabsorbable implant) completed the study. Mean patient age was 61.7 years +/- 10.9 (SD) (range 37 to 81) and did not differ among groups. Postoperative intraocular pressure (IOP) levels and visual acuity (logMAR values) did not differ among groups compared with preoperative levels. Average induced astigmatism was lower in the NPDS group than the trabeculectomy group at postoperative month 3 and 6 based on autokeratometry values (P =.023 and.042, respectively). Nonpenetrating surgeries resulted in less induced astigmatism in the early postoperative period and less against-the-rule shift over 6 months. CONCLUSION: Despite larger flap size and surgical area, nonpenetrating trabecular surgeries induced less astigmatism than trabeculectomy.

Adult↗

The effect of vernal keratoconjunctivitis on clinical outcomes of penetrating keratoplasty for keratoconus.

BACKGROUND: Although good visual results and low complication rates are commonly reported following penetrating keratoplasty (PKP) in eyes with keratoconus, the outcome of PKP in eyes with keratoconus and concomitant vernal keratoconjunctivitis (VKC) has not been well documented. We performed a study to compare the outcome and relative risk factors of PKP for keratoconus with and withoutVKC. METHODS: Review of the medical records of all patients who underwent PKP for keratoconus at a university-affiliated hospital in Izmir,Turkey, from Nov. 1, 1991, to Jan. 31, 2002. Only eyes that had been followed for at least 18 months postoperatively were included in the study. Twenty-three eyes of 19 patients (14 males and 5 females) had keratoconus with VKC, and 65 eyes of 57 patients (33 males and 24 females) had keratoconus alone. We compared clinical outcomes and complications between the two groups. RESULTS: The mean length of follow-up was 34.0 months (standard deviation [SD] 16.3 months) (range 18-67 months) in the eyes with comitant VKC and 41.0 (SD 19.8) months (range 18-98 months) in the eyes with keratoconus alone. During the follow-up period, 2.35 (SD 1.90) suture-removal sessions for loosened sutures were performed in the eyes with VKC, compared with 1.34 (SD 1.69) sessions in the eyes with keratoconus alone (p = 0.016). Steroid-induced glaucoma developed in two eyes (8.7%) in theVKC group and in three eyes (4.6%) in the keratoconus-alone group (p = 0.603); the rates of steroid-induced cataract were four (17.4%) and two (3.1%) respectively (p = 0.038). The average final best-corrected visual acuity was 20/22 (range 20/50 to 20/20) in the eyes with VKC and 20/23 (range 20/60 to 20/20) in the eyes with keratoconus alone. INTERPRETATION: The clinical outcome of PKP in eyes with keratoconus and VKC is comparable to that in eyes with keratoconus alone. However, because complications such as prematurely loosened sutures and steroid-induced cataract are more common in the coexistence of VKC, closer monitoring is necessary in these cases.

Adolescent↗

Comparison of cosmetic results in frontalis sling operations: the eyelid crease incision versus the supralash stab incision.

PURPOSE: In addition to ptosis, the lack of eyelid crease is one of the main cosmetic problems of patients with poor levator function. In this study, we aimed to evaluate the effect of the incision site on ptosis correction and eyelid crease formation in frontalis sling operations. MATERIALS AND METHODS: Photographs and charts of 27 patients (45 eyelids) who underwent frontalis sling operations were retrospectively reviewed. All patients had congenital ptosis with poor levator function ranging from 0 to 4 mm. In group I (15 eyelids), 3 supralash eyelid skin incisions were performed and the sling material was threaded along the tarsal surface. In group 11 (30 eyelids), the eyelid crease approach was used with the suturing of the sling material directly to the tarsus. RESULTS: Although lid contour and lid crease symmetry were good in 46.6% of the cases in group I, eyelid crease formation was not satisfactory in any of the cases. Lid contour and lid crease symmetry were good in 76.6% of the cases in group II. CONCLUSION: Our results indicated that the eyelid crease approach provided better functional and cosmetic results than did the supralash stab incision in frontalis sling operations. The passage of the sling material behind the orbital septum by direct visualization in the eyelid crease approach is one of the main factors affecting the surgical success of the frontalis sling operation.

Adolescent↗

Glaucoma implant surgery with autogenous fascia lata in scleromalacia perforans.

A 51-year-old woman with bilateral scleromalacia perforans and advanced glaucoma in the left eye was evaluated. Glaucoma implant surgery with autogenous fascia lata graft for reinforcement of the underlying sclera and a patch graft overlying the tube to prevent tube erosion was planned because of insufficient response to medical glaucoma therapy. Intraocular pressure decreased from 55 to 15 mm Hg and remained under 20 mm Hg throughout the follow-up period of 24 months. No complication was noted. Glaucoma implant surgery using autogenous fascia lata to form a healthy ground and a patch graft to prevent tube erosion seems to be a safe and effective method when normal sclera is lacking, such as in scleromalacia perforans.

Fascia Lata↗