Biomedical subjects

Avishai Henik

Publications and source records attributed to Avishai Henik.

At least 19 recordsLinked to original sources

PubMed2007

Notation-dependent and -independent representations of numbers in the parietal lobes.

It is a commonly held view that numbers are represented in an abstract way in both parietal lobes. This view is based on failures to find differences between various notational representations. Here we show that by using relatively smaller voxels together with an adaptation paradigm and analyzing subjects on an individual basis it is possible to detect specialized numerical representations. The current results reveal a left/right asymmetry in parietal lobe function. In contrast to an abstract representation in the left parietal lobe, the numerical representation in the right parietal lobe is notation dependent and thus includes nonabstract representations. Our results challenge the commonly held belief that numbers are represented solely in an abstract way in the human brain.

Adaptation, Physiological↗

PubMed2006

The effect of orientation on number word processing.

Besner and Coltheart [Besner, D., & Coltheart, M. (1979). Ideographic and alphabetic processing in skilled reading of English. Neuropsychologia, 17, 467-472] found a size congruity effect for Arabic numbers but not for number words. They proposed that Arabic numbers and number words are processed in different ways. However, in their study orientation of the stimuli and notation were confounded. In the present study, it is found that orientation of number words affects numerical processing. Orientation modulates both the size congruity effect and the distance effect; horizontal presentation produces similar results to those produced by Arabic numbers whereas vertical orientation produces different results. Accordingly, it is proposed that our cognitive system is endowed with two different mechanisms for numerical processing; one relies on a visual-spatial code and the other on a verbal code.

Adult↗

PubMed2006

Color congruity effect: where do colors and numbers interact in synesthesia?

The traditional size congruity paradigm is a Stroop-like situation where participants are asked to compare the values of two digits and ignore the irrelevant physical sizes of the digits (e.g., 3 5). Here a color congruity paradigm was employed and the irrelevant physical sizes were replaced by irrelevant colors. MM, a digit-color synesthete, yielded the classical congruity effect. Namely, she was slower to identify numerically larger numbers when they deviated from her synesthetic experience than when they matched it. In addition, the effect of color on her comparative judgments was modulated by numerical distance. In contrast, performance of non-synesthetes was not affected by the colors. On the basis of neurophysiological studies of magnitude comparison and interference between numerical and physical information, it is proposed that the interaction between colors and digits in MM occurs at the conceptual level. Moreover, by using the current paradigm it is possible to determine the stage at which color-digit binding in synesthesia occurs.

Adult↗

PubMed2006

A common representation for semantic and physical properties: a cognitive-anatomical approach.

This is the first report of a mutual interference between luminance and numerical value in magnitude judgments. Instead of manipulating the physical size of compared numbers, which is the traditional approach in size congruity studies, luminance levels were manipulated. The results yielded the classical congruity effect. Participants took more time to process numerically larger numbers when they were brighter than when they were darker, and more time to process a darker number when its numerical value was smaller than when it was larger. On the basis of neurophysiological studies of magnitude comparison and interference between semantic and physical information, it is proposed that the processing of semantic and physical magnitude information is carried out by a shared brain structure. It is suggested that this brain area, the left intraparietal sulcus, subserves various comparison processes by representing various quantities on an amodal magnitude scale.

Adult↗

PubMed2006

New data analysis of the stroop matching task calls for a reevaluation of theory.

In Stroop matching tasks, participants indicate whether the color of an object matches the meaning of a color word printed in color. Previously in this journal, Luo (1999) concluded that interference between two incongruent representations of the same attribute (ink color) occurs prior to the response stage. However, this conclusion was based on questionable data analysis. We suggest analyzing the data by separating "same" and "different" responses and then analyzing three congruency conditions within the "different" responses: (a) congruence between word color and word meaning, (b) congruence between word color and object color, and (c) incongruence between word color, word meaning, and object color. In an experiment similar to Luo's, such an analysis revealed that responding was slowest in the first condition. This pattern of results does not fit with previous conclusions regarding this task, but rather indicates that task conflict and response competition contribute to interference. This analysis has implications for matching tasks other than the Stroop matching task.

Color Perception↗

PubMed2006

Concreteness and context availability in lexical decision tasks.

Three experiments were carried out to elucidate the origins of the concreteness (C) effect in a lexical decision task. The first experiment was a replication of the work of Schwanenflugel et al. (1988) and Van Hell and De Groot (1998), who presented the context availability (CA) hypothesis. In this experiment CA seemed to be a dominant factor. Familiarity (FAM) was not incorporated in the ANOVA, but a regression analysis and negative correlation between C and FAM in the groups matched on CA showed that FAM could explain the disappearance of the C effect. Experiment 2 controlled FAM and revealed a C effect, although concrete and abstract words were matched on CA. Experiment 3 controlled C and FAM and revealed a CA effect. The current data emphasize the importance of controlling FAM and CA in examining the C effect in a lexical decision task and support a revised version of the dual-coding theory.

Comprehension↗

PubMed2005

Are numbers special? The comparison systems of the human brain investigated by fMRI.

Many studies have suggested that the intraparietal sulcus (IPS), particularly in the dominant hemisphere, is crucially involved in numerical comparisons. However, this parietal structure has been found to be involved in other tasks that require spatial processing or visuospatial attention as well. fMRI was used to investigate three different magnitude comparisons in an event-related-block design: (a) Which digit is larger in numerical value (e.g., 2 or 5)? (b) Which digit is brighter (e.g., 3 or 3)? (c) Which digit is physically larger (e.g., 3 or 3)? Results indicate a widespread cortical network including a bilateral activation of the intraparietal sulci for all different comparisons. However, by computing contrasts of brain activation between the respective comparison conditions and applying a cortical distance effect as an additional criterion, number-specific activation was revealed in left IPS and right temporal regions. These results indicate that there are both commonalities and differences in the spatial layout of the brain systems for numerical and physical comparisons and that especially the left IPS, while involved in magnitude comparison in general, plays a special role in number comparison.

Adult↗

PubMed2005

Competition between endogenous and exogenous orienting of visual attention.

The relation between reflexive and voluntary orienting of visual attention was investigated with 4 experiments: a simple detection task, a localization task, a saccade toward the target task, and a target identification task in which discrimination difficulty was manipulated. Endogenous and exogenous orienting cues were presented in each trial and their validity was manipulated orthogonally to examine whether attention mechanisms are mediated by separate systems and whether they have additive and independent effects on visual detection and discrimination. The results showed that each orienting mechanism developed its typical and independent effect in every case except for the difficult identification task. A theoretical framework for understanding the relationship between endogenous and exogenous orienting of attention is proposed, tested, and confirmed.

Attention↗

PubMed2005

Automatic activation of internal magnitudes: a study of developmental dyscalculia.

The association between Arabic numerals and the representations of magnitude in adult developmental dyscalculia was examined. University students compared physical size, vertical positioning (height), or grayness (different shades of gray) of 2 Arabic numerals. The numerical values could produce a Stroop-like numerical congruity effect (NCE; 3-5 vs. 3-5). The dyscalculia group did not show NCE in the grayness task, and their physical comparisons produced a significantly smaller NCE compared with that produced by the control group. Whereas previous research suggested that Arabic numerals activate representations of magnitude automatically, the results of this study indicate that this is not the case because (a) people with developmental dyscalculia require attention to associate internal representations of magnitude with Arabic numerals, and (b) activation of internal magnitudes depends on context (task).

Adolescent↗

PubMed2005

When blue is larger than red: colors influence numerical cognition in synesthesia.

In synesthesia, certain stimuli ("inducers") may give rise to perceptual experience in additional modalities not normally associated with them ("concurrent"). For example, color-grapheme synesthetes automatically perceive achromatic numbers as colored (e.g., 7 is turquoise). Although synesthetes know when a given color matches the one evoked by a certain number, colors do not automatically give rise to any sort of number experience. The behavioral consequences of synesthesia have been documented using Stroop-like paradigms, usually using color judgments. Owing to the unidirectional nature of the synesthetic experience, little has been done to obtain performance measures that could indicate whether bidirectional cross-activation occurs in synesthesia. Here it is shown that colors do implicitly evoke numerical magnitudes in color-grapheme synesthetes, but not in nonsynesthetic participants. It is proposed that bidirectional coactivation of brain areas is responsible for the links between color and magnitude processing in color-grapheme synesthesia and that unidirectional models of synesthesia might have to be revised.

Adult↗

PubMed2004

Differential processing of word and color in unilateral spatial neglect.

The aim of the present study was to investigate mechanisms underlying processing of contralesional visual stimuli in brain-damaged patients with unilateral spatial neglect (USN). Nine right-hemisphere-damaged stroke patients with left-sided neglect and nine controls performed a reaction-time task involving manual response to a central color patch (target stimulus) flanked to the left or right by a Stroop stimulus they had to ignore. While the word dimension of the flanker affected patients' responses considerably and equally when presented to either side, the color dimension of the flanker had no effect when presented to the left, but had a large effect when presented to the right. Four of the patients performed a control task requiring same/different judgments between either of the two flanker dimensions (color and word) and the central target. Their performance indicated that they were able to process color information from the contralesional field, despite their results in the first experiment. These findings demonstrate a dissociation between how the patients processed different dimensions of the same stimuli and imply that the extent of processing in the contralesional hemifield depends both on task requirements and on the exact features of the stimuli. The implications of these results on normal attentional mechanisms is also discussed.

Adult↗

PubMed2004

Role of disengagement failure and attentional gradient in unilateral spatial neglect - a longitudinal study.

PURPOSE: To assess the importance of 'disengagement failure' and 'attentional gradient' in unilateral spatial neglect (USN) and in recovery from neglect. METHOD: Eight right-hemisphere-damaged stroke patients performed the standardized Behavioural-Inattention-Test battery for visual neglect, line-bisection tests, and two computerized reaction-time (RT) tasks: a variant of Posner's 'Spatial-Cueing' paradigm (with special emphasis on the magnitude of leftward disengagement time) and a signal-detection task (marking the spatial gradient of attention by the distribution of RTs to target stimuli in different spatial locations). The correlation between the different measures was assessed at two points in time, before and after a period of rehabilitation treatment. RESULTS: A recovery pattern could be identified in both RT paradigms. However, the correlation between standard measures of neglect and performance on both, spatial-cueing and signal-detection tasks, was weak. CONCLUSION: Neither difficulty disengaging attention from an ipsilesional stimulus nor changes in the attentional gradient can fully explain the processes underlying USN and its recovery. A large interpersonal variance exists among USN patients in the expression of disengagement and other spatial-attention deficits. Hence, individual patients should be tested by measuring different factors known to play a role in USN. This information is crucial for assigning the appropriate treatment for each patient in accord with the specific deficit revealed.

Adult↗

PubMed2004

Parietal lobe lesions disrupt saccadic remapping of inhibitory location tagging.

Maintaining a coherent percept of the visual scene while eye position continuously changes requires that saccades be accompanied by remapping of the visual environment. We studied saccadic remapping in patients with unilateral lesions in the intraparietal sulcus and healthy controls, using inhibition of return (IOR)-an inhibitory tag that enables efficient visual search. In healthy controls, IOR was found at both retinal and environmental locations of the cue, indicating that the inhibitory tag had been remapped into environmental coordinates. In contrast, right parietal patients demonstrated IOR only at the retinal location of the cue, indicating that the intraparietal sulcus is involved in remapping of the environment after eye movements to afford a stable, environmentally based reference frame. Note that patients did not show environmental IOR in either visual field. These results also suggest that this region may be the neural substrate for encoding inhibitory spatial tags in an environmentally based reference frame.

Adult↗

PubMed2004

Schizophrenia and the stroop effect.

Conflict between irrelevant words and relevant colors in the Stroop task creates interference, long considered a measure of how well individuals focus attention. In the traditional card version of the Stroop task, schizophrenia patients exhibit increased interference, consistent with the distractibility they exhibit in everyday life. In contrast, on other versions of the Stroop task they show augmented facilitation (faster responding to congruent than to neutral trials). We suggest that schizophrenia patients possess adequate attentional resources to avoid interference when each letter string is presented individually but face difficulty when delays are imposed and multiple attentional demands appear. Although psychiatric symptomatology may contribute to different patterns of performance, there is no evidence that medication modulates this.

Affect↗

PubMed2003

Is there a "strength effect" in automatic semantic priming?

According to spreading activation models of automatic priming, highly related associates should yield stronger priming effects than weakly related associates. The strength of relations is usually based on word association norms. However, this strength effect has been found in some studies but not in others. The present study suggests that one factor that might be responsible for this inconsistency is whether the weak associate is the primary or nonprimary response in the word association norms This possibility was explored by comparing priming effects of weak nonprimary and primary associates with those of strong primary associates. Comparable priming effects were found for the strong and weak primary associates whereas the weak nonprimary associates did not yield any priming effects. These results were obtained both in paired (Experiment 1) and single (Experiment 2) presentation priming procedures. Thus, the rank of the associate is an important factor in predicting the magnitude of the priming effect.

Automatism↗

PubMed2003

Auditory imagery from musical notation in expert musicians.

Anecdotal evidence has suggested that musical notation can trigger auditory images. Expert musicians silently read scores containing well-known themes embedded into the notation of an embellished phrase and judged if a tune heard aloud thereafter was the original theme (i.e., melodic target) or not (i.e., melodic lure). Three experiments were conducted employing four score-reading conditions: normal nondistracted reading, concurrent rhythmic distraction, phonatory interference, and obstruction by auditory stimuli. The findings demonstrate that phonatory interference impaired recognition of original themes more than did the other conditions. We propose that notational audiation is the silent reading of musical notation resulting in auditory imagery. The research suggests that it also elicits kinesthetic-like phonatory processes.

Adolescent↗

PubMed2002

Electroencephalographic activity in a flanker interference task using Japanese orthography.

The neural activities for color word interference effects were investigated using event-related brain potentials (ERPs) recorded in a flanker-type interference task. Kanji words (Japanese morphograms) and kana words (Japanese phonograms) were used as the flanker stimuli to obtain insights about hemispheric specialization for processing two types of Japanese orthographies. Interference effects in reaction time were larger when kanji words were presented in the left visual field and when kana words were in the right visual field. ERPs were modulated by the incongruent flankers, which generated a negative ERP component with the different onset and offset depending on flanker attributes. Consistent with the behavioral data, the interference-related negativity was observed for kanji words presented in the left visual field and for kana words in the right visual field. The negativity distributed maximally over the fronto-central site. The early part of the negativity distributed strongly over the frontal midline area, whereas it extended bilaterally over the frontal area in the late phase. The present results support the view of preferential processing of kanji in the right hemisphere and that of kana in the left hemisphere. The temporal profile of scalp topographies for the interference-related neural activity suggests that the medial and dorsolateral prefrontal regions may be involved in maintaining attentional set and conflict resolution.

Adult↗

PubMed2002

Preliminary evidence of reduced cognitive inhibition in methamphetamine-dependent individuals.

Chronic methamphetamine abuse is associated with disruption of frontostriatal function involving serotonin and dopamine circuitry. Clinically, methamphetamine-dependent (MD) individuals are highly distractible and have difficulty focussing. Here, we used a computerized single-trial version of the Stroop Test to examine selective attention and priming in MD. Subject groups comprised eight MD men (31.7+/-7.2 years of age), who had used methamphetamine for 15.75+/-8.4 years but were currently abstinent for 2-4 months, and 12 controls (35.7+9.7 years of age). Compared with the control group, the MD group exhibited significantly greater interference (P<0.05) despite intact priming. Error rates did not differ between the groups. This preliminary finding of reduced cognitive inhibition in MD individuals is consistent with the distractibility they show clinically. Furthermore, the dissociation between explicit attentional performance and priming effects suggests that some attentional functions are not as affected by long-term methamphetamine use as others.

Adult↗