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Biomedical subjects

Anthony D Woolf

Publications and source records attributed to Anthony D Woolf.

5 recordsLinked to original sources
PubMed2003

Radiographic damage associated with low bone mineral density and vertebral deformities in rheumatoid arthritis: the Oslo-Truro-Amsterdam (OSTRA) collaborative study.

OBJECTIVE: To examine variables associated with bone mineral density (BMD) and vertebral deformities in women with rheumatoid arthritis (RA) from 3 northwest European countries. METHODS: Female patients were recruited from rheumatology clinics in Oslo, Norway; Truro, UK; and Amsterdam, The Netherlands (150 total, 50 per center, age 50-70 years, disease duration > or = 5 years). Demographic and clinical data were collected and BMD was measured by means of dual energy x-ray absorptiometry. Associations between demographic and clinical measures on the one hand and BMD and vertebral deformities on the other were investigated by single and multiple regression analyses. RESULTS: Body mass index (BMI), medication use, RA damage measures, and BMD differed significantly between the 3 centers. Overall, Norwegian patients had the lowest BMI, used more corticosteroids and anti-osteoporotic drugs, had lower joint damage measured by Larsen score, and lower BMD at both spine and hip. High age, low BMI, and high cumulative dose of corticosteroids (last 2 years) are related to low BMD. A high Larsen score was associated with low BMD at the hip. Larsen score was the independent determinant of vertebral deformities after correction for center, age, BMI, and BMD. CONCLUSION: Data from 3 countries on BMD and vertebral deformities in female patients aged 50-70 years with longstanding RA are presented, demonstrating an association between radiographic RA damage and low BMD and between radiographic RA damage and vertebral deformities.

Absorptiometry, Photon↗
PubMed2003

How to assess musculoskeletal conditions. History and physical examination.

Musculoskeletal conditions are common, their impact is pervasive and they are a major burden on health and social care. However, they are poorly managed because of lack of priority and inadequate competencies due to limited medical education in this spectrum of conditions. The ability to take a clear history and perform a competent examination are core skills to the appropriate management of musculoskeletal problems. This chapter outlines an approach that is followed by most specialists in rheumatology, orthopaedics or rehabilitation that can be used to teach other clinicians going into primary care or at the beginning of specialist training.

Clinical Competence↗
PubMed2003

The bone and joint decade. strategies to reduce the burden of disease: the Bone and Joint Monitor Project.

Musculoskeletal conditions are the major cause of morbidity and substantially influence health and quality of life, with enormous costs to health systems. This article describes the Bone and Joint Monitor Project, whose objective is to provide evidence to enable development of policies and strategies to improve the prevention and treatment of musculoskeletal conditions, relevant to their geographic and socioeconomic settings. By identifying the burden of disease and establishing strategies that can be implemented in routine clinical practice, musculoskeletal conditions can be managed more effectively and progress can be demonstrated through the establishment of routine health monitoring. With the interventions currently available, it is feasible that all people will be afforded the right to pain control, mobility, and independence.

Global Health↗