Careers in systems biology. A meeting of minds, expertise, and imagination.
Explore the source record for details and available documents.
Career Choice↗
Biomedical subjects
Anne Forde
Publications and source records attributed to Anne Forde.
The class of 2005. Germany: deciphering cellular processes.
Biochemist Anne Spang will soon take up her first tenured faculty position--a professorship--at the Biozentrum in Basel, Switzerland. Her research career has taken her to four countries, where she has investigated fundamental cell biological questions.
Biomedical Research↗
The class of 2005. Norway: a neuroscientist making connections.
A clinician by training, Farrukh A. Chaudhry's passion for basic science has taken him across the Atlantic, where he discovered a new family of neurological amino acid transporters. Last August, he just started his first faculty position at the Biotechnology Centre in Oslo.
Academies and Institutes↗
The class of 2005: Germany. Tracking pollutants.
Next year, German environmental chemist Martin Elsner will move from Toronto to the GSF National Research Centre for Environment and Health near Munich to take up his first tenure-track position as a Helmholtz Young Investigator.
Career Choice↗
Keys to Independence in the U.K. and Ireland.
Funding bodies are coming to the aid of young scientists with a variety of programs aimed at helping them become independent investigators.
Career Mobility↗
Views From the Trenches.
Making the transition from postdoc to independent investigator is tough. Scientists who received prestigious fellowships or grants relate their experiences-and offer some advice.
Biomedical Research↗
Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements.
SUMMARY: The versatility of the bacteriophage Cre/LoxP system is dependent on the availability of a spectrum of tissue-specific Cre transgenic mice to address a host of biological questions. In this paper, we report on the generation of an inducible Tie2Cre transgenic mouse line that facilitates gene targeting exclusively in endothelial cells. The temporal manner of recombination is feasible through the use of a Cre-estrogen receptor fusion protein ER(T2) and was, in practical terms, achieved by feeding the animals the estrogen antagonist tamoxifen orally for 5 weeks. High efficiency of recombination was found in the vast majority of endothelial cell populations examined, as monitored by an EGFP reporter mouse line. Critically, no EGFP expression was observed in any uninduced mice. This inducible Cre line will be a very beneficial asset to investigating the role of endothelial specific genes in the adult mouse and to induce transgenes in the endothelium in an extremely efficient manner. genesis 33:191-197, 2002.
Animals↗