Primitive neuroectodermal tumors.
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Adult↗
Biomedical subjects
Anita M Borges
Publications and source records attributed to Anita M Borges.
Aggressive behaviour of solid arrangement pattern in differentiated papillary carcinoma of thyroid.
The prognosis and overall outcome of solid growth pattern in differentiated papillary carcinoma of thyroid is controversial. While general consensus suggest outcomes similar to typical papillary carcinomas others demonstrate a more aggressive biology. We present a case of differentiated papillary carcinoma of thyroid with solid growth pattern presenting with neck swelling and widespread skeletal metastases. The areas of bone lesions showed avid 131I concentration on a postoperative large dose 131I whole body scan and was treated with 131I subsequently. The present case suggest that the solid architecture in a papillary thyroid carcinoma may be indicative of an aggressive clinical course, contrary to the common opinion that it does not adversely influence its biologic behaviour and thus emphasize the need to reexplore the prognostic significance of histopathologic subclassification along with an assessment of histologic grade and expression of molecular risk factors in this particular tumour subtype.
Adenocarcinoma↗
The prevalence of high-grade prostatic intraepithelial neoplasia in surgical resection specimens: an Indian experience.
BACKGROUND: To the authors' knowledge there is a paucity of literature regarding the prevalence of high-grade prostatic intraepithelial neoplasia (HGPIN) in the Indian subcontinent. The objective of the current study was to document the prevalence of HGPIN in a low-risk Indian population. METHOD: SA total of 110 prostate specimens (61 taken from the test group and 49 taken from the control group) were studied to document the prevalence of HGPIN in a low-risk Indian population. RESULTS: None of the benign prostate samples were found to harbor HGPIN, whereas 85.24% of the samples from malignant prostates did so. CONCLUSION: SA strong correlation between HGPIN and invasive carcinoma was observed, a finding that reinforces the view that HGPIN is a strong indicator of concurrent invasive prostate carcinoma.
Humans↗